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ORNL researchers, from left, Yang Liu, Xiaohan Yang and Torik Islam, collaborated on the development of a new capability to insert multiple genes simultaneously for fast, efficient transformation of plants into better bioenergy feedstocks. Credit: Genevieve Martin/ORNL, U.S. Dept. of Energy

In a discovery aimed at accelerating the development of process-advantaged crops for jet biofuels, scientists at ORNL developed a capability to insert multiple genes into plants in a single step.

ORNL scientists mutated amino acids in a receptor protein, shown in green, which diminished interaction with the SARS-CoV-2 virus spike protein, shown in red. Mutating the receptor protein hampered the virus’s ability to infect host cells. Credit: ORNL, U.S. Dept. of Energy

Oak Ridge National Laboratory scientists exploring bioenergy plant genetics have made a surprising discovery: a protein domain that could lead to new COVID-19 treatments.

Oak Ridge National Laboratory led a team of scientists to design a molecule that disrupts the infection mechanism of the SARS-CoV-2 coronavirus and could be used to develop new treatments for COVID-19 and future virus outbreaks. Credit: Michelle Lehman/ORNL, U.S. Dept. of Energy

A team of scientists led by the Department of Energy’s Oak Ridge National Laboratory designed a molecule that disrupts the infection mechanism of the SARS-CoV-2 coronavirus and could be used to develop new treatments for COVID-19 and other viral diseases.

The licensing and leadership team behind AMIGO. Credit: Carlos Jones/ORNL, U.S. Dept. of Energy

A technology developed at ORNL and used by the U.S. Naval Information Warfare Systems Command, or NAVWAR, to test the capabilities of commercial security tools has been licensed to cybersecurity firm Penguin Mustache to create its Evasive.ai platform. The company was founded by the technology’s creator, former ORNL scientist Jared M. Smith, and his business partner, entrepreneur Brandon Bruce.

A new license to U2opia pairs two technologies developed in ORNL’s Cyber Resilience and Intelligence Division: Situ and Heartbeat. Credit: ORNL, U.S. Dept. of Energy

U2opia Technology, a consortium of technology and administrative executives with extensive experience in both industry and defense, has exclusively licensed two technologies from ORNL that offer a new method for advanced cybersecurity monitoring in real time.

Computational systems biologists at ORNL worked with the U.S. Department of Veterans Affairs and other institutions to identify 139 locations across the human genome tied to risk factors for varicose veins, marking a first step in the development of new treatments. Credit: Andy Sproles/ORNL, U.S. Dept. of Energy

As part of a multi-institutional research project, scientists at ORNL leveraged their computational systems biology expertise and the largest, most diverse set of health data to date to explore the genetic basis of varicose veins.

A team led by Raymond Borges Hink has developed a method using blockchain to protect communications between electronic devices in the electric grid, preventing cyberattacks and cascading blackouts. Credit: Genevieve Martin/ORNL, U.S. Dept. of Energy

Although blockchain is best known for securing digital currency payments, researchers at the Department of Energy’s Oak Ridge National Laboratory are using it to track a different kind of exchange: It’s the first time blockchain has ever been used to validate communication among devices on the electric grid.

Michelle Kidder received the lab’s Director’s Award for Outstanding Individual Accomplishment in Science and Technology for her decades-long work mentoring students, teachers and early-career staff. Credit: Carlos Jones/ORNL, U.S. Dept. of Energy

Laboratory Director Thomas Zacharia presented five Director’s Awards during Saturday night's annual Awards Night event hosted by UT-Battelle, which manages ORNL for the Department of Energy.

This image from Sept. 30, 2022, shows how the Federal Emergency Management Agency used ORNL's USA Structures data along with new satellite images to identify structures that were destroyed in Lee County, Florida, during Hurricane Ian. Credit: ORNL, U.S. Dept. of Energy

Over the past seven years, researchers in ORNL’s Geospatial Science and Human Security Division have mapped and characterized all structures within the United States and its territories to aid FEMA in its response to disasters. This dataset provides a consistent, nationwide accounting of the buildings where people reside and work.

Researchers at Oak Ridge National Laboratory probed the chemistry of radium to gain key insights on advancing cancer treatments using radiation therapy. Credit: Adam Malin/ORNL, U.S. Dept. of Energy

Researchers at ORNL explored radium’s chemistry to advance cancer treatments using ionizing radiation.