Filter News
Area of Research
News Type
News Topics
- (-) Biomedical (5)
- (-) Coronavirus (5)
- 3-D Printing/Advanced Manufacturing (4)
- Advanced Reactors (1)
- Artificial Intelligence (7)
- Big Data (1)
- Bioenergy (4)
- Biology (5)
- Biotechnology (1)
- Chemical Sciences (2)
- Climate Change (1)
- Composites (1)
- Computer Science (13)
- Cybersecurity (9)
- Decarbonization (1)
- Energy Storage (3)
- Environment (4)
- Exascale Computing (1)
- Frontier (2)
- Fusion (2)
- Grid (1)
- High-Performance Computing (2)
- Machine Learning (4)
- Materials (7)
- Materials Science (13)
- Microscopy (1)
- Nanotechnology (6)
- National Security (11)
- Neutron Science (40)
- Nuclear Energy (2)
- Partnerships (4)
- Physics (8)
- Quantum Science (4)
- Security (6)
- Space Exploration (1)
- Summit (4)
- Sustainable Energy (2)
- Transportation (3)
Media Contacts
A team of scientists led by the Department of Energy’s Oak Ridge National Laboratory designed a molecule that disrupts the infection mechanism of the SARS-CoV-2 coronavirus and could be used to develop new treatments for COVID-19 and other viral diseases.
ORNL scientists will present new technologies available for licensing during the annual Technology Innovation Showcase. The event is 9 a.m. to 3 p.m. Thursday, June 16, at the Manufacturing Demonstration Facility at ORNL’s Hardin Valley campus.
Scientists have found new, unexpected behaviors when SARS-CoV-2 – the virus that causes COVID-19 – encounters drugs known as inhibitors, which bind to certain components of the virus and block its ability to reproduce.
Experiments led by researchers at ORNL have determined that several hepatitis C drugs can inhibit the SARS-CoV-2 main protease, a crucial protein enzyme that enables the novel coronavirus to reproduce.
To better understand how the novel coronavirus behaves and how it can be stopped, scientists have completed a three-dimensional map that reveals the location of every atom in an enzyme molecule critical to SARS-CoV-2 reproduction.
A team of researchers has performed the first room-temperature X-ray measurements on the SARS-CoV-2 main protease — the enzyme that enables the virus to reproduce.
OAK RIDGE, Tenn., March 20, 2019—Direct observations of the structure and catalytic mechanism of a prototypical kinase enzyme—protein kinase A or PKA—will provide researchers and drug developers with significantly enhanced abilities to understand and treat fatal diseases and neurological disorders such as cancer, diabetes, and cystic fibrosis.