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Neutron scattering experiments show electric charges, shown in red, blue and grey, in the SARS-CoV-2 main protease site where telaprevir binds to the structure. The experiments provide critical data for the design of small-molecule drugs to treat COVID-19. Credit: Jill Hemman and Michelle Lehman/ORNL, U.S. Dept. of Energy

Scientists have found new, unexpected behaviors when SARS-CoV-2 – the virus that causes COVID-19 – encounters drugs known as inhibitors, which bind to certain components of the virus and block its ability to reproduce.  

 The researchers embedded a programmable model into a D-Wave quantum computer chip. Credit: D-Wave

A multi-institutional team became the first to generate accurate results from materials science simulations on a quantum computer that can be verified with neutron scattering experiments and other practical techniques.

ORNL recognized the small businesses that have made a positive impact on ORNL’s operations at the virtual 2020 Small Business Awards. Credit: ORNL, U.S. Dept. of Energy

Thirty-two Oak Ridge National Laboratory employees were named among teams recognized by former DOE Secretary Dan Brouillette with Secretary’s Honor Awards as he completed his term. Four teams received new awards that reflect DOE responses to the coronavirus pandemic.

Merlin Theodore holding N95 mask filtration material produced at DOE's Carbon Fiber Technology Facility

Three technologies developed by ORNL researchers have won National Technology Transfer Awards from the Federal Laboratory Consortium. One of the awards went to a team that adapted melt-blowing capabilities at DOE’s Carbon Fiber Technology Facility to enable the production of filter material for N95 masks in the fight against COVID-19.

Brian Damiano

Brian Damiano, head of the Centrifuge Engineering and Fabrication Section, has been elected fellow of the American Society of Mechanical Engineers.

Six ORNL scientists have been elected as fellows to the American Association for the Advancement of Science, or AAAS. Credit: ORNL, U.S. Dept. of Energy

Six ORNL scientists have been elected as fellows to the American Association for the Advancement of Science, or AAAS.

David Kropaczek

David Kropaczek, director of the Consortium for Advanced Simulation of Light Water Reactors, or CASL, at the Department of Energy’s Oak Ridge National Laboratory, has been named a fellow of the American Nuclear Society.

ORNL Sign

Seven ORNL scientists have been named among the 2020 Highly Cited Researchers list, according to Clarivate, a data analytics firm that specializes in scientific and academic research.

New virtual tours of ORNL facilities include the Building Technologies Research and Integration Center, shown in dollhouse view. Credit: ORNL, U.S. Dept. of Energy

ORNL has added 10 virtual tours to its campus map, each with multiple views to show floor plans, rotating dollhouse views and 360-degree navigation. As a user travels through a map, pop-out informational windows deliver facts, videos, graphics and links to other related content.

The first neutron structure of the SARS-CoV-2 main protease enzyme revealed unexpected electrical charges in the amino acids cysteine (negative) and histidine (positive), providing key data about the virus’s replication. Credit: Jill Hemman/ORNL, U.S. Dept. of Energy

To better understand how the novel coronavirus behaves and how it can be stopped, scientists have completed a three-dimensional map that reveals the location of every atom in an enzyme molecule critical to SARS-CoV-2 reproduction.