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Sergei Kalinin

Five researchers at the Department of Energy’s Oak Ridge National Laboratory have been named ORNL Corporate Fellows in recognition of significant career accomplishments and continued leadership in their scientific fields.

Selenium atoms, represented by orange, implant in a monolayer of blue tungsten and yellow sulfur to form a Janus layer. In the background, electron microscopy confirms atomic positions. Credit: Oak Ridge National Laboratory, U.S. Dept. of Energy

An ORNL team used a simple process to implant atoms precisely into the top layers of ultra-thin crystals, yielding two-sided structures with different chemical compositions.

The protease protein is both shaped like a heart and functions as one, allowing the virus replicate and spread. Inhibiting the protease would block virus reproduction. Credit: Andrey Kovalevsky/ORNL, U.S. Dept. of Energy

A team of researchers has performed the first room-temperature X-ray measurements on the SARS-CoV-2 main protease — the enzyme that enables the virus to reproduce.

ORNL welcomes six new research fellows to Innovation Crossroads

ORNL welcomed six technology innovators to join the fourth cohort of Innovation Crossroads, the Southeast’s only entrepreneurial research and development program based at a U.S. Department of Energy national laboratory.

A nanobrush made by pulsed laser deposition of CeO2 and Y2O3 with dim and bright bands, respectively, is seen in cross-section with scanning transmission electron microscopy. Credit: Oak Ridge National Laboratory, U.S. Dept. of Energy

A team led by the Department of Energy’s Oak Ridge National Laboratory synthesized a tiny structure with high surface area and discovered how its unique architecture drives ions across interfaces to transport energy or information.

Coronavirus research

Researchers at the Department of Energy’s Oak Ridge National Laboratory have used Summit, the world’s most powerful and smartest supercomputer, to identify 77 small-molecule drug compounds that might warrant further study in the fight

Gobet_Advincula Portrait

Rigoberto “Gobet” Advincula has been named Governor’s Chair of Advanced and Nanostructured Materials at Oak Ridge National Laboratory and the University of Tennessee.

Illustration of the intricate organization of the PKA structure, wherein different parts of the protein are connected through elaborate hydrogen bonding networks (dashed yellow lines), glued together by the hydrophobic assemblies (light blue and orange volumes)—all working together to build the functional active site. Insert shows protonation of the transferred phosphoryl group (cyan mesh) and its many interactions with water and the active site amino acid residues. Credit: Jill Hemman/ORNL

OAK RIDGE, Tenn., March 20, 2019—Direct observations of the structure and catalytic mechanism of a prototypical kinase enzyme—protein kinase A or PKA—will provide researchers and drug developers with significantly enhanced abilities to understand and treat fatal diseases and neurological disorders such as cancer, diabetes, and cystic fibrosis.

(From left) ORNL Associate Laboratory Director for Computing and Computational Sciences Jeff Nichols; ORNL Health Data Sciences Institute Director Gina Tourassi; DOE Deputy Under Secretary for Science Thomas Cubbage; ORNL Task Lead for Biostatistics Blair Christian; and ORNL Research Scientist Ioana Danciu were invited to the White House to showcase an ORNL-developed digital tool aimed at better matching cancer patients with clinical trials.

OAK RIDGE, Tenn., March 4, 2019—A team of researchers from the Department of Energy’s Oak Ridge National Laboratory Health Data Sciences Institute have harnessed the power of artificial intelligence to better match cancer patients with clinical trials.

Sean Hearne has been named director of the Center for Nanophase Materials Sciences at Oak Ridge National Laboratory.

OAK RIDGE, Tenn., Feb. 8, 2019—The Department of Energy’s Oak Ridge National Laboratory has named Sean Hearne director of the Center for Nanophase Materials Sciences. The center is a DOE Office of Science User Facility that brings world-leading resources and capabilities to the nanoscience resear...