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Neutron experiments helped reveal the one-carbon enzymatic mechanism that synthesizes vital food sources for cancer cells that depend on vitamin B6, providing key insights into designing novel drugs to slow the spread of aggressive cancers. Credit: Jill Hemman/ORNL, U.S. Dept. of Energy

After a highly lauded research campaign that successfully redesigned a hepatitis C drug into one of the leading drug treatments for COVID-19, scientists at ORNL are now turning their drug design approach toward cancer. 

Upgrades to the particle accelerator enabling the record 1.7-megawatt beam power at the Spallation Neutron Source included adding 28 high-power radio-frequency klystrons (red tubes) to provide higher power for the accelerator. Credit: Genevieve Martin/ORNL, U.S. Dept. of Energy

The Spallation Neutron Source at the Department of Energy's Oak Ridge National Laboratory set a world record when its particle accelerator beam operating power reached 1.7 megawatts, substantially improving on the facility’s original design capability.

Rigoberto Advincula

Rigoberto Advincula, a renowned scientist at ORNL and professor of Chemical and Biomolecular Engineering at the University of Tennessee, has won the Netzsch North American Thermal Analysis Society Fellows Award for 2023.

ytterbium

ORNL’s electromagnetic isotope separator, or EMIS, made history in 2018 when it produced 500 milligrams of the rare isotope ruthenium-96, unavailable anywhere else in the world. 

Jason Gardner, Sandra Davern and Peter Thornton have been elected fellows of AAAS. Credit: Laddy Fields/ORNL, U.S. Dept. of Energy

Three scientists from the Department of Energy’s Oak Ridge National Laboratory have been elected fellows of the American Association for the Advancement of Science, or AAAS.

Paul Langan will oversee ORNL's research directorate focused on biological and environmental systems science. Credit: ORNL, U.S. Dept. of Energy

Paul Langan will join ORNL in the spring as associate laboratory director for the Biological and Environmental Systems Science Directorate.

A pure lipid membrane formed using lipid-coated water droplets exhibits long-term potentiation, or LTP, associated with learning and memory, emulating hippocampal LTP observed in the brains of mammals and birds. Credit: Jill Hemman/ORNL, U.S. Dept. of Energy

While studying how bio-inspired materials might inform the design of next-generation computers, scientists at ORNL achieved a first-of-its-kind result that could have big implications for both edge computing and human health.

Nearly $500 million in Inflation Reduction Act funding will support several key science projects underway at ORNL. Credit: ORNL/U.S. Dept. of Energy

Several significant science and energy projects led by the ORNL will receive a total of $497 million in funding from the Inflation Reduction Act.

U.S. Secretary of Energy Jennifer Granholm visited Oak Ridge National Laboratory today to attend a groundbreaking ceremony for the U.S. Stable Isotope Research and Development Center. The facility is slated to receive $75 million in funding from the Inflation Reduction Act.

U.S. Secretary of Energy Jennifer Granholm visited Oak Ridge National Laboratory today to attend a groundbreaking ceremony for the U.S. Stable Isotope Production and Research Center. The facility is slated to receive $75 million in funding from the Inflation Reduction Act.

ORNL’s Valentino Cooper will direct a new DOE Energy Frontier Research Center focused on polymer electrolytes for solid-state batteries. Credit: Carlos Jones/ORNL, U.S. Dept. of Energy

ORNL has been selected to lead an Energy Frontier Research Center, or EFRC, focused on polymer electrolytes for next-generation energy storage devices such as fuel cells and solid-state electric vehicle batteries.