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Media Contacts
![The protease protein is both shaped like a heart and functions as one, allowing the virus replicate and spread. Inhibiting the protease would block virus reproduction. Credit: Andrey Kovalevsky/ORNL, U.S. Dept. of Energy](/sites/default/files/styles/list_page_thumbnail/public/2020-06/protease_dimer_3_1.png?h=aa51a450&itok=sJY7AB8d)
A team of researchers has performed the first room-temperature X-ray measurements on the SARS-CoV-2 main protease — the enzyme that enables the virus to reproduce.
![Solid radium sulfate sits in the bottom of a flask during the recovery process. Credit: Oak Ridge National Laboratory, U.S. Dept. of Energy](/sites/default/files/styles/list_page_thumbnail/public/2020-06/Ac227%202.jpg?h=479d286c&itok=AiNceGva)
Oak Ridge National Laboratory researchers have discovered a better way to separate actinium-227, a rare isotope essential for an FDA-approved cancer treatment.
![Transformational Challenge Reactor Demonstration items](/sites/default/files/styles/list_page_thumbnail/public/2020-03/Press_release_image.jpg?h=b707efd5&itok=-Sxbmt8D)
Researchers at the Department of Energy’s Oak Ridge National Laboratory are refining their design of a 3D-printed nuclear reactor core, scaling up the additive manufacturing process necessary to build it, and developing methods
![Nuclear – Finally, a benchmark](/sites/default/files/styles/list_page_thumbnail/public/2020-05/67051_0.jpg?h=add82d74&itok=xR-EnPtz)
In the 1960s, Oak Ridge National Laboratory's four-year Molten Salt Reactor Experiment tested the viability of liquid fuel reactors for commercial power generation. Results from that historic experiment recently became the basis for the first-ever molten salt reactor benchmark.
![Closely spaced hydrogen atoms could facilitate superconductivity in ambient conditions](/sites/default/files/styles/list_page_thumbnail/public/2020-02/Closely_spaced_hydrogen_atoms-correct.png?h=6a4c2577&itok=GBnxpWls)
An international team of researchers has discovered the hydrogen atoms in a metal hydride material are much more tightly spaced than had been predicted for decades — a feature that could possibly facilitate superconductivity at or near room temperature and pressure.
![Argon pellet injection text](/sites/default/files/styles/list_page_thumbnail/public/2019-11/13966_Ar_20degree_enhanced_0.jpg?h=8450e950&itok=tmff0GX_)
As scientists study approaches to best sustain a fusion reactor, a team led by Oak Ridge National Laboratory investigated injecting shattered argon pellets into a super-hot plasma, when needed, to protect the reactor’s interior wall from high-energy runaway electrons.
![Nuclear—Tiny testing fuels](/sites/default/files/styles/list_page_thumbnail/public/2019-05/MiniFuel_2019-P03618_0.jpg?h=49ab6177&itok=VVYMAZ3E)
For the first time, Oak Ridge National Laboratory has completed testing of nuclear fuels using MiniFuel, an irradiation vehicle that allows for rapid experimentation.
![Materials—Engineering heat transport](/sites/default/files/styles/list_page_thumbnail/public/2019-05/Materials-Engineering_heat_transport.png?h=abd215d5&itok=PJPSWa9s)
Scientists have discovered a way to alter heat transport in thermoelectric materials, a finding that may ultimately improve energy efficiency as the materials
![Snowflakes indicate phases of super-cold ice](/sites/default/files/styles/list_page_thumbnail/public/2019-05/19-G00404_Tulk_PR_0.jpg?h=e4fbc3eb&itok=5fn8aUhP)
An ORNL-led team's observation of certain crystalline ice phases challenges accepted theories about super-cooled water and non-crystalline ice. Their findings, reported in the journal Nature, will also lead to better understanding of ice and its various phases found on other planets, moons and elsewhere in space.
![Illustration of the intricate organization of the PKA structure, wherein different parts of the protein are connected through elaborate hydrogen bonding networks (dashed yellow lines), glued together by the hydrophobic assemblies (light blue and orange volumes)—all working together to build the functional active site. Insert shows protonation of the transferred phosphoryl group (cyan mesh) and its many interactions with water and the active site amino acid residues. Credit: Jill Hemman/ORNL](/sites/default/files/styles/list_page_thumbnail/public/2019-03/19-G00204_MR_graphic_Kovalevsky_proof5_2.png?h=b7fbb1a9&itok=wrZFNX-o)
OAK RIDGE, Tenn., March 20, 2019—Direct observations of the structure and catalytic mechanism of a prototypical kinase enzyme—protein kinase A or PKA—will provide researchers and drug developers with significantly enhanced abilities to understand and treat fatal diseases and neurological disorders such as cancer, diabetes, and cystic fibrosis.