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Media Contacts
![Ashleigh Kimberlin and Mikayla Molnar achieve success with a gas-trapping apparatus for Ac-225 production. Credit: ORNL, U.S. Dept. of Energy](/sites/default/files/styles/list_page_thumbnail/public/2021-11/Acgastrapping-1.png?h=71976bb4&itok=TbfsnNxp)
In experiment after experiment, the synthetic radioisotope actinium-225 has shown promise for targeting and attacking certain types of cancer cells.
![Targeted alpha therapy can deliver radiation to specific cells, with minimal effect on surrounding, healthy cells. Credit: Michelle Lehman and Jaimee Janiga/ORNL, U.S. Dept. of Energy](/sites/default/files/2021-03/gif_high_res.gif)
A rare isotope in high demand for treating cancer is now more available to pharmaceutical companies developing and testing new drugs.
![Neutron scattering experiments show electric charges, shown in red, blue and grey, in the SARS-CoV-2 main protease site where telaprevir binds to the structure. The experiments provide critical data for the design of small-molecule drugs to treat COVID-19. Credit: Jill Hemman and Michelle Lehman/ORNL, U.S. Dept. of Energy](/sites/default/files/styles/list_page_thumbnail/public/2021-03/after_transprent_background-wFill.png?h=c71d0c67&itok=jGFt_Ggj)
Scientists have found new, unexpected behaviors when SARS-CoV-2 – the virus that causes COVID-19 – encounters drugs known as inhibitors, which bind to certain components of the virus and block its ability to reproduce.
![Oak Ridge National Laboratory entrance sign](/themes/custom/ornl/images/default-thumbnail.jpg)
Balendra Sutharshan, deputy associate laboratory director for operational systems at DOE’s Pacific Northwest National Laboratory, has joined ORNL as associate laboratory director for the Isotope Science and Engineering Directorate.
![Brian Damiano](/sites/default/files/styles/list_page_thumbnail/public/2020-12/2016-P04442.jpg?h=49ab6177&itok=lPIC-H6L)
Brian Damiano, head of the Centrifuge Engineering and Fabrication Section, has been elected fellow of the American Society of Mechanical Engineers.
![ORNL is designing a neutronic research engine to evaluate new materials and designs for advanced vehicles using the facilities at the Spallation Neutron Source at ORNL. Credit: Jill Hemman/ORNL, U.S. Dept of Energy, and Southwest Research Institute.](/sites/default/files/styles/list_page_thumbnail/public/2020-12/20-G01771_VULCAN_engine_proof1.png?h=e4fbc3eb&itok=f6owlGkE)
In the quest for advanced vehicles with higher energy efficiency and ultra-low emissions, ORNL researchers are accelerating a research engine that gives scientists and engineers an unprecedented view inside the atomic-level workings of combustion engines in real time.
![An organic solvent and water separate and form nanoclusters on the hydrophobic and hydrophilic sections of plant material, driving the efficient deconstruction of biomass. Credit: Michelle Lehman/ORNL, U.S. Dept. of Energy](/sites/default/files/styles/list_page_thumbnail/public/2020-11/dark_image_small.png?h=2e111cc1&itok=drKqW05b)
Experiments led by researchers at ORNL have determined that several hepatitis C drugs can inhibit the SARS-CoV-2 main protease, a crucial protein enzyme that enables the novel coronavirus to reproduce.
![The first neutron structure of the SARS-CoV-2 main protease enzyme revealed unexpected electrical charges in the amino acids cysteine (negative) and histidine (positive), providing key data about the virus’s replication. Credit: Jill Hemman/ORNL, U.S. Dept. of Energy](/sites/default/files/styles/list_page_thumbnail/public/2020-10/20-G01620_Protease_PR_proof2_0.jpg?h=3e3883a3&itok=XB_ZEDFQ)
To better understand how the novel coronavirus behaves and how it can be stopped, scientists have completed a three-dimensional map that reveals the location of every atom in an enzyme molecule critical to SARS-CoV-2 reproduction.
![Cations between layers of MXene](/sites/default/files/styles/list_page_thumbnail/public/2020-08/Cations_holistic_study_0.png?h=de4bb2b8&itok=gX7Dgpbe)
A team led by Oak Ridge National Laboratory developed a novel, integrated approach to track energy-transporting ions within an ultra-thin material, which could unlock its energy storage potential leading toward faster charging, longer-lasting devices.
![An organic solvent and water separate and form nanoclusters on the hydrophobic and hydrophilic sections of plant material, driving the efficient deconstruction of biomass. Credit: Michelle Lehman/ORNL, U.S. Dept. of Energy](/sites/default/files/2020-07/THF_high_res.gif)
Scientists at ORNL used neutron scattering and supercomputing to better understand how an organic solvent and water work together to break down plant biomass, creating a pathway to significantly improve the production of renewable