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Media Contacts
![Illustration of the intricate organization of the PKA structure, wherein different parts of the protein are connected through elaborate hydrogen bonding networks (dashed yellow lines), glued together by the hydrophobic assemblies (light blue and orange volumes)—all working together to build the functional active site. Insert shows protonation of the transferred phosphoryl group (cyan mesh) and its many interactions with water and the active site amino acid residues. Credit: Jill Hemman/ORNL](/sites/default/files/styles/list_page_thumbnail/public/2019-03/19-G00204_MR_graphic_Kovalevsky_proof5_2.png?h=b7fbb1a9&itok=wrZFNX-o)
OAK RIDGE, Tenn., March 20, 2019—Direct observations of the structure and catalytic mechanism of a prototypical kinase enzyme—protein kinase A or PKA—will provide researchers and drug developers with significantly enhanced abilities to understand and treat fatal diseases and neurological disorders such as cancer, diabetes, and cystic fibrosis.
![Neutron scattering allowed direct observation of how aurein induces lateral segregation in the bacteria membranes, which creates instability in the membrane structure. This instability causes the membranes to fail, making harmful bacteria less effective.](/sites/default/files/styles/list_page_thumbnail/public/2019-03/Neutrons-FightingSuperbugs_0.jpg?h=e4b73f5a&itok=ebOQD-Mr)
As the rise of antibiotic-resistant bacteria known as superbugs threatens public health, Oak Ridge National Laboratory’s Shuo Qian and Veerendra Sharma from the Bhaba Atomic Research Centre in India are using neutron scattering to study how an antibacterial peptide interacts with and fights harmful bacteria.
![(From left) ORNL Associate Laboratory Director for Computing and Computational Sciences Jeff Nichols; ORNL Health Data Sciences Institute Director Gina Tourassi; DOE Deputy Under Secretary for Science Thomas Cubbage; ORNL Task Lead for Biostatistics Blair Christian; and ORNL Research Scientist Ioana Danciu were invited to the White House to showcase an ORNL-developed digital tool aimed at better matching cancer patients with clinical trials.](/sites/default/files/styles/list_page_thumbnail/public/2019-03/TourassiWH%5B1%5D.png?h=26b5064d&itok=HUC2iYmE)
OAK RIDGE, Tenn., March 4, 2019—A team of researchers from the Department of Energy’s Oak Ridge National Laboratory Health Data Sciences Institute have harnessed the power of artificial intelligence to better match cancer patients with clinical trials.
![carbon nanospikes carbon nanospikes](/sites/default/files/styles/list_page_thumbnail/public/carbon_nanospikes.jpg?itok=D0GNAvH4)
OAK RIDGE, Tenn., March 1, 2019—ReactWell, LLC, has licensed a novel waste-to-fuel technology from the Department of Energy’s Oak Ridge National Laboratory to improve energy conversion methods for cleaner, more efficient oil and gas, chemical and
![As part of a preliminary study, ORNL scientists used critical location data collected from Twitter to map the location of certain power outages across the United States.](/sites/default/files/styles/list_page_thumbnail/public/2019-02/PowerOutageTweets_map_0.png?h=6448fdc1&itok=AUit-O2Y)
Gleaning valuable data from social platforms such as Twitter—particularly to map out critical location information during emergencies— has become more effective and efficient thanks to Oak Ridge National Laboratory.
![An ORNL-developed graphite foam, which could be used in plasma-facing components in fusion reactors, performed well during testing at the Wendlestein 7-X stellarator in Germany.](/sites/default/files/styles/list_page_thumbnail/public/2019-02/W7-XPlasmaExposure_0.jpg?h=d5d04e3b&itok=uKiauhdF)
Scientists have tested a novel heat-shielding graphite foam, originally created at Oak Ridge National Laboratory, at Germany’s Wendelstein 7-X stellarator with promising results for use in plasma-facing components of fusion reactors.
OAK RIDGE, Tenn., Feb. 12, 2019—A team of researchers from the Department of Energy’s Oak Ridge and Los Alamos National Laboratories has partnered with EPB, a Chattanooga utility and telecommunications company, to demonstrate the effectiveness of metro-scale quantum key distribution (QKD).
![ORNL scientists used commuting behavior data from East Tennessee to demonstrate how machine learning models can easily accept new data, quickly re-train themselves and update predictions about commuting patterns. Credit: April Morton/Oak Ridge National La ORNL scientists used commuting behavior data from East Tennessee to demonstrate how machine learning models can easily accept new data, quickly re-train themselves and update predictions about commuting patterns. Credit: April Morton/Oak Ridge National La](/sites/default/files/styles/list_page_thumbnail/public/study_area_one_dest_2.jpg?itok=2cWFkQvW)
Oak Ridge National Laboratory geospatial scientists who study the movement of people are using advanced machine learning methods to better predict home-to-work commuting patterns.
![Nuclear—Deep space travel Nuclear—Deep space travel](/sites/default/files/styles/list_page_thumbnail/public/Screen%20Shot%202018-12-19%20at%2010.29.32%20AM.png?itok=hq0dlVIf)
By automating the production of neptunium oxide-aluminum pellets, Oak Ridge National Laboratory scientists have eliminated a key bottleneck when producing plutonium-238 used by NASA to fuel deep space exploration.
![Using as much as 50 percent lignin by weight, a new composite material created at ORNL is well suited for use in 3D printing. Using as much as 50 percent lignin by weight, a new composite material created at ORNL is well suited for use in 3D printing.](/sites/default/files/styles/list_page_thumbnail/public/2018-P09551.jpg?itok=q7Ri01Qb)
Scientists at the Department of Energy’s Oak Ridge National Laboratory have created a recipe for a renewable 3D printing feedstock that could spur a profitable new use for an intractable biorefinery byproduct: lignin.