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ORNL researchers led by Michael Garvin, left, and David Kainer discovered genetic mutations called structural variants and linked them to autism spectrum disorders, demonstrating an approach that could be used to develop better diagnostics and drug therapies. Credit: Carlos Jones/ORNL, U.S. Dept. of Energy

ORNL researchers discovered genetic mutations that underlie autism using a new approach that could lead to better diagnostics and drug therapies.

Researchers at ORNL designed a recyclable carbon fiber material to promote low-carbon manufacturing. Credit: Chad Malone/ORNL, U.S. Dept. of Energy

Oak Ridge National Laboratory scientists designed a recyclable polymer for carbon-fiber composites to enable circular manufacturing of parts that boost energy efficiency in automotive, wind power and aerospace applications.

Matthew Craig’s research at ORNL is focused on how carbon cycles in and out of soils, a process that can have tremendous impact on the Earth’s climate. Credit: Carlos Jones/ORNL, U.S. Dept. of Energy

Matthew Craig grew up eagerly exploring the forest patches and knee-high waterfalls just beyond his backyard in central Illinois’ corn belt. Today, that natural curiosity and the expertise he’s cultivated in biogeochemistry and ecology are focused on how carbon cycles in and out of soils, a process that can have tremendous impact on the Earth’s climate.

ORNL’s Tomás Rush explores the secret lives of fungi and plants for insights into the interactions that determine plant health. Credit: Genevieve Martin/ORNL, U.S. Dept. of Energy

Tomás Rush began studying the mysteries of fungi in fifth grade and spent his college intern days tromping through forests, swamps and agricultural lands searching for signs of fungal plant pathogens causing disease on host plants.

Scientists used genome sequencing and computational biology to tease out the genetic profile of a new moss species, Sphagnum magni, typically found in the southeastern United States. Credit: Blanka Aguero, Duke University

A team from Oak Ridge National Laboratory, Duke University and other institutions studying Sphagnum moss have identified two new species in North America, and they are learning how evolution may affect the species’ role in carbon storage.

Distinguished staff fellow Gang Seob “GS” Jung knew from an early age he wanted to be a scientist. Credit: Carlos Jones/ORNL, U.S. Dept. of Energy

Gang Seob “GS” Jung has known from the time he was in middle school that he was interested in science.

Researchers used quantum Monte Carlo calculations to accurately render the structure and electronic properties of germanium selenide, a semiconducting nanomaterial. Credit: Paul Kent/ORNL, U.S. Dept. of Energy

A multi-lab research team led by ORNL's Paul Kent is developing a computer application called QMCPACK to enable precise and reliable predictions of the fundamental properties of materials critical in energy research.

A team of researchers used mathematics to predict which areas of the SARS-CoV-2 spike protein are most likely to mutate. Credit: Jill Hemman/ORNL, U.S. Dept. of Energy

Researchers from ORNL, the University of Tennessee at Chattanooga and Tuskegee University used mathematics to predict which areas of the SARS-CoV-2 spike protein are most likely to mutate.

The ORNL and Cummins CRADA led to the development of the R&D 100 Award-winning SpaciMS diagnostic tool that enabled researchers to gain a better understanding of reactor and catalytic chemistry. Credit: ORNL, U.S. Dept. of Energy

When Bill Partridge started working with industry partner Cummins in 1997, he was a postdoctoral researcher specializing in applied optical diagnostics and new to Oak Ridge National Laboratory.

ORNL physicist Libby Johnson demonstrated a new control panel at ORNL’s Bulk Shielding Facility in 1957. Among the first females to operate a nuclear reactor, Johnson blazed trails for women. Credit: ORNL, U.S. Dept. of Energy

Oak Ridge National Laboratory physicist Elizabeth “Libby” Johnson (1921-1996), one of the world’s first nuclear reactor operators, standardized the field of criticality safety with peers from ORNL and Los Alamos National Laboratory.