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Scientists conducted microbial DNA sampling at a Yellowstone National Park hot spring for a study sponsored by DOE’s Biological and Environmental Research program, the National Science Foundation and NASA. Credit: Mircea Podar/ORNL, U.S. Dept. of Energy

Oak Ridge National Laboratory scientists studied hot springs on different continents and found similarities in how some microbes adapted despite their geographic diversity.

ORNL scientists mutated amino acids in a receptor protein, shown in green, which diminished interaction with the SARS-CoV-2 virus spike protein, shown in red. Mutating the receptor protein hampered the virus’s ability to infect host cells. Credit: ORNL, U.S. Dept. of Energy

Oak Ridge National Laboratory scientists exploring bioenergy plant genetics have made a surprising discovery: a protein domain that could lead to new COVID-19 treatments.

Researchers at Oak Ridge National Laboratory probed the chemistry of radium to gain key insights on advancing cancer treatments using radiation therapy. Credit: Adam Malin/ORNL, U.S. Dept. of Energy

Researchers at ORNL explored radium’s chemistry to advance cancer treatments using ionizing radiation.

With seismic and acoustic data recorded by remote sensors near ORNL’s High Flux Isotope Reactor, researchers could predict whether the reactor was on or off with 98% accuracy. Credit: Nathan Armistead/ORNL, U.S. Dept. of Energy

An Oak Ridge National Laboratory team developed a novel technique using sensors to monitor seismic and acoustic activity and machine learning to differentiate operational activities at facilities from “noise” in the recorded data.

Genetic analysis revealed connections between inflammatory activity and development of atomic dermatitis, according to researchers from the UPenn School of Medicine, the Perelman School of Medicine, and Oak Ridge National Laboratory. Credit: Kang Ko/UPenn

University of Pennsylvania researchers called on computational systems biology expertise at Oak Ridge National Laboratory to analyze large datasets of single-cell RNA sequencing from skin samples afflicted with atopic dermatitis.

The first central solenoid module arrived at the ITER site in St. Paul-lez-Durance, France on Sept. 9. Credit: ITER Organization

Staff at Oak Ridge National Laboratory organized transport for a powerful component that is critical to the world’s largest experiment, the international ITER project.

Initially, Kevin Gaddis’s adapted HPIC will be used only for the fourth of six separations in  actinium-225 processing, but he hopes it will later be used for other separations — and other isotopes. Credit: Carlos Jones/ORNL, U.S. Dept. of Energy

An Oak Ridge National Laboratory researcher has invented a version of an isotope-separating device that can withstand extreme environments, including radiation and chemical solvents.

Scientists genetically engineered bacteria for itaconic acid production, creating dynamic controls that separate microbial growth and production phases for increased efficiency and acid yield. Credit: NREL

A research team led by Oak Ridge National Laboratory bioengineered a microbe to efficiently turn waste into itaconic acid, an industrial chemical used in plastics and paints.

ORNL welder Devin Johnson uses a new orbital welder to seal a hollow target in a glovebox in the lab’s Radiochemical Engineering Development Center. The new welder makes a clean seam on the metal target, eliminating the need for hand-finishing afterward. Credit: Carlos Jones/ORNL, U.S. Dept. of Energy

A better way of welding targets for Oak Ridge National Laboratory’s plutonium-238 production has sped up the process and improved consistency and efficiency. This advancement will ultimately benefit the lab’s goal to make enough Pu-238 – the isotope that powers NASA’s deep space missions – to yield 1.5 kilograms of plutonium oxide annually by 2026.

An ORNL researcher holds a capsule of molten salt. Preliminary experiments seem to indicate that irradiation can slow corrosion of metal in liquid salt. Credit: ORNL, U.S. Dept. of Energy

Irradiation may slow corrosion of alloys in molten salt, a team of Oak Ridge National Laboratory scientists has found in preliminary tests.