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ORNL scientists mutated amino acids in a receptor protein, shown in green, which diminished interaction with the SARS-CoV-2 virus spike protein, shown in red. Mutating the receptor protein hampered the virus’s ability to infect host cells. Credit: ORNL, U.S. Dept. of Energy

Oak Ridge National Laboratory scientists exploring bioenergy plant genetics have made a surprising discovery: a protein domain that could lead to new COVID-19 treatments.

When an electron beam drills holes in heated graphene, single-atom vacancies, shown in purple, diffuse until they join with other vacancies to form stationary structures and chains, shown in blue. Credit: Ondrej Dyck/ORNL, U.S. Dept. of Energy

Oak Ridge National Laboratory researchers serendipitously discovered when they automated the beam of an electron microscope to precisely drill holes in the atomically thin lattice of graphene, the drilled holes closed up.

A team of researchers used mathematics to predict which areas of the SARS-CoV-2 spike protein are most likely to mutate. Credit: Jill Hemman/ORNL, U.S. Dept. of Energy

Researchers from ORNL, the University of Tennessee at Chattanooga and Tuskegee University used mathematics to predict which areas of the SARS-CoV-2 spike protein are most likely to mutate.

Oak Ridge National Laboratory researchers quantified human behaviors during the early days of COVID-19, which could be useful for disaster response or city planning. Credit: Nathan Armistead/ORNL, U.S. Dept. of Energy

Researchers at Oak Ridge National Laboratory have empirically quantified the shifts in routine daytime activities, such as getting a morning coffee or takeaway dinner, following safer at home orders during the early days of the COVID-19 pandemic.

Researchers at Oak Ridge National Laboratory demonstrated center-of-mass scanning transmission electron microscopy to observe lithium along with heavier elements in battery materials at atomic resolution. Credit: Chad Malone/ORNL, U.S. Dept. of Energy

Oak Ridge National Laboratory researchers demonstrated an electron microscopy technique for imaging lithium in energy storage materials, such as lithium ion batteries, at the atomic scale.

Scientists, from left, Parans Paranthaman, Tina Summers and Merlin Theodore at the DOE’s Carbon Fiber Technology Facility at ORNL are partnering with industry and university to develop antiviral materials for N95 masks. Credit: Genevieve Martin/ORNL, U.S. Dept. of Energy

Oak Ridge National Laboratory researchers collaborated with Iowa State University and RJ Lee Group to demonstrate a safe and effective antiviral coating for N95 masks. The coating destroys the COVID-19-causing coronavirus and could enable reuse of masks made from various fabrics.

ORNL researchers proved that COVID-19 vaccines can be kept ultra-cool for an extended period in a retrofitted commercial storage container, providing a resource for safe delivery to remote locations. Credit: ORNL, U.S. Dept. of Energy

Oak Ridge National Laboratory researchers have retrofitted a commercial refrigeration container designed to ensure COVID-19 vaccines remain at ultra-low temperatures during long transport and while locally stored.

ORNL’s Eva Zarkadoula seeks piezoelectric materials for sensors that can withstand irradiation, which causes cascading collisions that displace atoms and produces defects. Credit: Carlos Jones/ORNL, U.S. Dept. of Energy

To advance sensor technologies, Oak Ridge National Laboratory researchers studied piezoelectric materials, which convert mechanical stress into electrical energy, to see how they could handle bombardment with energetic neutrons.

Researchers used an atomic force microscope to test how easily particles of the novel coronavirus cling to certain surfaces, a property known as adhesion energy. Credit: Ali Passian/ORNL, U.S. Dept. of Energy

A study by Department of Energy researchers detailed a potential method to detect the novel coronavirus

Researchers built optical tools called zero-mode waveguides, illustrated here, used to observe proteins that are implicated in human heart function. Credit: David S. White/University of Wisconsin-Madison

Researchers working with Oak Ridge National Laboratory developed a new method to observe how proteins, at the single-molecule level, bind with other molecules and more accurately pinpoint certain molecular behavior in complex