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Genetic analysis revealed connections between inflammatory activity and development of atomic dermatitis, according to researchers from the UPenn School of Medicine, the Perelman School of Medicine, and Oak Ridge National Laboratory. Credit: Kang Ko/UPenn

University of Pennsylvania researchers called on computational systems biology expertise at Oak Ridge National Laboratory to analyze large datasets of single-cell RNA sequencing from skin samples afflicted with atopic dermatitis.

ORNL’s Brenda Pracheil, left, and Kristine Moody collect water samples at Melton Hill Lake using a sophisticated instrument that collects DNA in the water to determine fish species and number of fish in the water, which could prove useful for monitoring hydropower impacts. Credit: Carlos Jones, ORNL/U.S Dept. of Energy

Researchers at Oak Ridge National Laboratory are using a novel approach in determining environmental impacts to aquatic species near hydropower facilities, potentially leading to smarter facility designs that can support electrical grid reliability.

A new process developed by Oak Ridge National Laboratory leverages deep learning techniques to study cell movements in a simulated environment, guided by simple physics rules similar to video-game play. Credit: MSKCC and UTK

Scientists have developed a novel approach to computationally infer previously undetected behaviors within complex biological environments by analyzing live, time-lapsed images that show the positioning of embryonic cells in C. elegans, or roundworms. Their published methods could be used to reveal hidden biological activity. 

ORNL is making underused or inaccessible bioenergy data available to accelerate innovation for the bioeconomy. Credit: Andy Sproles/ORNL, U.S. Dept. of Energy

A research team from Oak Ridge National Laboratory has identified and improved the usability of data that can help accelerate innovation for the growing bioeconomy.

Planting native grasses such as the bioenergy crop switchgrass can restore habitat for birds like this Eastern kingbird. Credit: Chris Lituma/West Virginia University

An analysis by Oak Ridge National Laboratory shows that using less-profitable farmland to grow bioenergy crops such as switchgrass could fuel not only clean energy, but also gains in biodiversity.

In a study, ORNL researchers concluded that the most direct path to plastic upcycling is through designing polymers specifically for reuse, which would allow the material to be converted into high-value products. Credit: Andy Sproles/ORNL, U.S. Dept. of Energy

Oak Ridge National Laboratory researchers determined that designing polymers specifically with upcycling in mind could reduce future plastic waste considerably and facilitate a circular economy where the material is used repeatedly.

ORNL researchers used a laser power bed manufacturing technique to 3D print a lightweight aluminum and cerium-based alloy that can withstand temperatures up to 300 degrees Celsius, proving high strength and durability for automotive, aerospace and defense applications. Credit: ORNL, U.S. Dept. of Energy

Oak Ridge National Laboratory researchers have additively manufactured a lightweight aluminum alloy and demonstrated its ability to resist creep or deformation at 300 degrees Celsius.

ORNL researchers developed a novel process for manufacturing extreme heat resistant carbon-carbon composites at a faster rate and produced fins or strakes made of the materials for testing on a U.S. Navy rocket launching with NASA. Credit: ORNL, Sandia/U.S. Dept. of Energy

Oak Ridge National Laboratory researchers have developed a novel process to manufacture extreme heat resistant carbon-carbon composites. The performance of these materials will be tested in a U.S. Navy rocket that NASA will launch this fall.

The first central solenoid module arrived at the ITER site in St. Paul-lez-Durance, France on Sept. 9. Credit: ITER Organization

Staff at Oak Ridge National Laboratory organized transport for a powerful component that is critical to the world’s largest experiment, the international ITER project.

The ectomycorrhizal fungus Laccaria bicolor, shown in green, envelops the roots of a transgenic switchgrass plant. Switchgrass is not known to interact with this type of fungi naturally; the added PtLecRLK1 gene tells the plant to engage the fungus. Credit: ORNL, U.S. Dept. of Energy

An ORNL team has successfully introduced a poplar gene into switchgrass, an important biofuel source, that allows switchgrass to interact with a beneficial fungus, ultimately boosting the grass’ growth and viability in changing environments.