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Hybrid poplar trees such as these shown in an ORNL greenhouse were engineered with the REVEILLE1 gene to delay dormancy and produce more biomass. The research was led by the Center for Bioenergy Innovation at ORNL with the Joint Genome Institute, Brookhaven National Laboratory, the HudsonAlpha Institute for Biotechnology, the University of Connecticut and other partners. Credit: Genevieve Martin/ORNL, U.S. Dept. of Energy

A team of scientists led by ORNL discovered the gene in agave that governs when the plant goes dormant and used it to create poplar trees that nearly doubled in size, increasing biomass yield for biofuels production

ORNL researchers led by Michael Garvin, left, and David Kainer discovered genetic mutations called structural variants and linked them to autism spectrum disorders, demonstrating an approach that could be used to develop better diagnostics and drug therapies. Credit: Carlos Jones/ORNL, U.S. Dept. of Energy

ORNL researchers discovered genetic mutations that underlie autism using a new approach that could lead to better diagnostics and drug therapies.

Scientists used genome sequencing and computational biology to tease out the genetic profile of a new moss species, Sphagnum magni, typically found in the southeastern United States. Credit: Blanka Aguero, Duke University

A team from Oak Ridge National Laboratory, Duke University and other institutions studying Sphagnum moss have identified two new species in North America, and they are learning how evolution may affect the species’ role in carbon storage.

Researchers used quantum Monte Carlo calculations to accurately render the structure and electronic properties of germanium selenide, a semiconducting nanomaterial. Credit: Paul Kent/ORNL, U.S. Dept. of Energy

A multi-lab research team led by ORNL's Paul Kent is developing a computer application called QMCPACK to enable precise and reliable predictions of the fundamental properties of materials critical in energy research.

Thylakoid

A team of scientists led by Oak Ridge National Laboratory developed a theory that thylakoids, membrane networks key to plant photosynthesis, also function as a defense mechanism to harsh growing conditions, which could aid the development of hardier plants.

The AI-driven HyperCT platform has three primary points of articulation that can rotate a sample in almost any direction, eliminating the need for human intervention and significantly reducing lengthy experiment times. Credit: Genevieve Martin, ORNL/U.S. Dept. of Energy

Oak Ridge National Laboratory researchers are developing a first-of-its-kind artificial intelligence device for neutron scattering called Hyperspectral Computed Tomography, or HyperCT.

Oak Ridge National Laboratory researchers developed an invertible neural network, a type of artificial intelligence that mimics the human brain, to improve accuracy in climate-change models and predictions. Credit: Getty Images

Oak Ridge National Laboratory researchers developed an invertible neural network, a type of artificial intelligence that mimics the human brain, to improve accuracy in climate-change models and predictions.

Genetic analysis revealed connections between inflammatory activity and development of atomic dermatitis, according to researchers from the UPenn School of Medicine, the Perelman School of Medicine, and Oak Ridge National Laboratory. Credit: Kang Ko/UPenn

University of Pennsylvania researchers called on computational systems biology expertise at Oak Ridge National Laboratory to analyze large datasets of single-cell RNA sequencing from skin samples afflicted with atopic dermatitis.

A new process developed by Oak Ridge National Laboratory leverages deep learning techniques to study cell movements in a simulated environment, guided by simple physics rules similar to video-game play. Credit: MSKCC and UTK

Scientists have developed a novel approach to computationally infer previously undetected behaviors within complex biological environments by analyzing live, time-lapsed images that show the positioning of embryonic cells in C. elegans, or roundworms. Their published methods could be used to reveal hidden biological activity. 

ORNL’s Eva Zarkadoula seeks piezoelectric materials for sensors that can withstand irradiation, which causes cascading collisions that displace atoms and produces defects. Credit: Carlos Jones/ORNL, U.S. Dept. of Energy

To advance sensor technologies, Oak Ridge National Laboratory researchers studied piezoelectric materials, which convert mechanical stress into electrical energy, to see how they could handle bombardment with energetic neutrons.