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Media Contacts
![The protease protein is both shaped like a heart and functions as one, allowing the virus replicate and spread. Inhibiting the protease would block virus reproduction. Credit: Andrey Kovalevsky/ORNL, U.S. Dept. of Energy](/sites/default/files/styles/list_page_thumbnail/public/2020-06/protease_dimer_3_1.png?h=aa51a450&itok=sJY7AB8d)
A team of researchers has performed the first room-temperature X-ray measurements on the SARS-CoV-2 main protease — the enzyme that enables the virus to reproduce.
![Computing – Mining for COVID-19 connections](/sites/default/files/styles/list_page_thumbnail/public/2020-05/pubmedconnections-covid-19-2_0.png?h=3dbd9eac&itok=NPdQ3tCD)
Scientists have tapped the immense power of the Summit supercomputer at Oak Ridge National Laboratory to comb through millions of medical journal articles to identify potential vaccines, drugs and effective measures that could suppress or stop the
![Before the demonstration, the team prepared QKD equipment (pictured) at ORNL. Image credit: Genevieve Martin/Oak Ridge National Laboratory, U.S. Dept. of Energy](/sites/default/files/styles/list_page_thumbnail/public/2020-05/2020-P01652_0.jpg?h=c6980913&itok=qHZPZfd6)
For the second year in a row, a team from the Department of Energy’s Oak Ridge and Los Alamos national laboratories led a demonstration hosted by EPB, a community-based utility and telecommunications company serving Chattanooga, Tennessee.
![Coronavirus graphic](/sites/default/files/styles/list_page_thumbnail/public/2020-04/covid19_jh_0.png?h=d1cb525d&itok=PyngFUZw)
In the race to identify solutions to the COVID-19 pandemic, researchers at the Department of Energy’s Oak Ridge National Laboratory are joining the fight by applying expertise in computational science, advanced manufacturing, data science and neutron science.
![The agreement builds upon years of collaboration, including a 2016 effort using modeling tools developed at ORNL to predict the first six months of operations of TVA’s Watts Bar Unit 2 nuclear power plant. Credit: Andrew Godfrey/Oak Ridge National Laboratory, U.S. Dept. of Energy](/sites/default/files/styles/list_page_thumbnail/public/2020-02/wb2_xenon_1.png?h=19940d61&itok=Da4pDLde)
OAK RIDGE, Tenn., Feb. 19, 2020 — The U.S. Department of Energy’s Oak Ridge National Laboratory and the Tennessee Valley Authority have signed a memorandum of understanding to evaluate a new generation of flexible, cost-effective advanced nuclear reactors.
![The image visualizes how the team’s multitask convolutional neural network classifies primary cancer sites. Image credit: Hong-Jun Yoon/ORNL](/sites/default/files/styles/list_page_thumbnail/public/2020-02/shot_0.png?h=49ab6177&itok=IXL5Ingy)
As the second-leading cause of death in the United States, cancer is a public health crisis that afflicts nearly one in two people during their lifetime.
![ORNL’s collaboration with Cincinati Children’s Hospital Medical Center will leverage the lab’s expertise in high-performance computing and safe, secure recordkeeping. Credit: Genevieve Martin/Oak Ridge National Laboratory, U.S. Dept. of Energy](/sites/default/files/styles/list_page_thumbnail/public/2020-02/CADES2019-P00182.jpg?h=c6980913&itok=P-o1DBeT)
Oak Ridge National Laboratory will partner with Cincinnati Children’s Hospital Medical Center to explore ways to deploy expertise in health data science that could more quickly identify patients’ mental health risk factors and aid in
![Small modular reactor computer simulation](/sites/default/files/styles/list_page_thumbnail/public/2019-04/Nuclear_simulation_scale-up.jpg?h=5992a83f&itok=A0oscIPL)
In a step toward advancing small modular nuclear reactor designs, scientists at Oak Ridge National Laboratory have run reactor simulations on ORNL supercomputer Summit with greater-than-expected computational efficiency.
![ORNL staff members (from left) Ashley Shields, Michael Galloway, Ketan Maheshwari and Andrew Miskowiec are collaborating on a project focused on predicting and analyzing crystal structures of new uranium oxide phases. Credit: Jason Richards/ORNL](/sites/default/files/styles/list_page_thumbnail/public/2019-03/teamphotoforhighlight_0.jpg?h=a00326b7&itok=O4yDtVj6)
Scientists at the Department of Energy’s Oak Ridge National Laboratory are working to understand both the complex nature of uranium and the various oxide forms it can take during processing steps that might occur throughout the nuclear fuel cycle.
![Molecular dynamics simulations of the Fs-peptide revealed the presence of at least eight distinct intermediate stages during the process of protein folding. The image depicts a fully folded helix (1), various transitional forms (2–8), and one misfolded state (9). By studying these protein folding pathways, scientists hope to identify underlying factors that affect human health.](/sites/default/files/styles/list_page_thumbnail/public/2019-03/Slide1_0.png?h=c855054e&itok=aNbgxXsc)
Using artificial neural networks designed to emulate the inner workings of the human brain, deep-learning algorithms deftly peruse and analyze large quantities of data. Applying this technique to science problems can help unearth historically elusive solutions.