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![Molecular dynamics simulations of the Fs-peptide revealed the presence of at least eight distinct intermediate stages during the process of protein folding. The image depicts a fully folded helix (1), various transitional forms (2–8), and one misfolded state (9). By studying these protein folding pathways, scientists hope to identify underlying factors that affect human health.](/sites/default/files/styles/list_page_thumbnail/public/2019-03/Slide1_0.png?h=c855054e&itok=aNbgxXsc)
Using artificial neural networks designed to emulate the inner workings of the human brain, deep-learning algorithms deftly peruse and analyze large quantities of data. Applying this technique to science problems can help unearth historically elusive solutions.
![ORNL-led collaboration solves a beta-decay puzzle with advanced nuclear models](/sites/default/files/styles/list_page_thumbnail/public/2019-03/decay_coverSize_4%5B21%5D_0.jpg?h=843037ec&itok=BU6x1GD8)
OAK RIDGE, Tenn., March 11, 2019—An international collaboration including scientists at the Department of Energy’s Oak Ridge National Laboratory solved a 50-year-old puzzle that explains why beta decays of atomic nuclei
![(From left) ORNL Associate Laboratory Director for Computing and Computational Sciences Jeff Nichols; ORNL Health Data Sciences Institute Director Gina Tourassi; DOE Deputy Under Secretary for Science Thomas Cubbage; ORNL Task Lead for Biostatistics Blair Christian; and ORNL Research Scientist Ioana Danciu were invited to the White House to showcase an ORNL-developed digital tool aimed at better matching cancer patients with clinical trials.](/sites/default/files/styles/list_page_thumbnail/public/2019-03/TourassiWH%5B1%5D.png?h=26b5064d&itok=HUC2iYmE)
OAK RIDGE, Tenn., March 4, 2019—A team of researchers from the Department of Energy’s Oak Ridge National Laboratory Health Data Sciences Institute have harnessed the power of artificial intelligence to better match cancer patients with clinical trials.
![Researchers used machine learning methods on the ORNL Compute and Data Environment for Science, or CADES, to map vegetation communities in the Kougarok Watershed on the Seward Peninsula of Alaska. The colors denote different types of vegetation, such as w Researchers used machine learning methods on the ORNL Compute and Data Environment for Science, or CADES, to map vegetation communities in the Kougarok Watershed on the Seward Peninsula of Alaska. The colors denote different types of vegetation, such as w](/sites/default/files/styles/list_page_thumbnail/public/rs2019_highlight_plot_3d.png?itok=5bROV_ys)
A team of scientists led by Oak Ridge National Laboratory used machine learning methods to generate a high-resolution map of vegetation growing in the remote reaches of the Alaskan tundra.
![Coexpression_hi-res_image[1].jpg Coexpression_hi-res_image[1].jpg](/sites/default/files/styles/list_page_thumbnail/public/Coexpression_hi-res_image%5B1%5D_0.jpg?itok=OnLe-krT)
While studying the genes in poplar trees that control callus formation, scientists at Oak Ridge National Laboratory have uncovered genetic networks at the root of tumor formation in several human cancers.
![Supercomputing-Memory_boost1.jpg Supercomputing-Memory_boost1.jpg](/sites/default/files/styles/list_page_thumbnail/public/Supercomputing-Memory_boost1.jpg?itok=dDR8CnYC)
Scientists at Oak Ridge National Laboratory and Hypres, a digital superconductor company, have tested a novel cryogenic, or low-temperature, memory cell circuit design that may boost memory storage while using less energy in future exascale and quantum computing applications.
![Oak Ridge National Laboratory’s Summit supercomputer was named No. 1 on the TOP500 List, a semiannual ranking of the world’s fastest computing systems. Credit: Carlos Jones/Oak Ridge National Laboratory, U.S. Dept. of Energy.Oak Ridge National Laboratory’ Oak Ridge National Laboratory’s Summit supercomputer was named No. 1 on the TOP500 List, a semiannual ranking of the world’s fastest computing systems. Credit: Carlos Jones/Oak Ridge National Laboratory, U.S. Dept. of Energy.](/sites/default/files/styles/list_page_thumbnail/public/2018-P03971.jpg?itok=BNeaoWKB)
The US Department of Energy’s Oak Ridge National Laboratory is once again officially home to the fastest supercomputer in the world, according to the TOP500 List, a semiannual ranking of the world’s fastest computing systems.
![Oak Ridge National Laboratory launches Summit supercomputer. Oak Ridge National Laboratory launches Summit supercomputer.](/sites/default/files/styles/list_page_thumbnail/public/2018-P01537.jpg?itok=GLf4y1EZ)
The U.S. Department of Energy’s Oak Ridge National Laboratory today unveiled Summit as the world’s most powerful and smartest scientific supercomputer.
![Radiochemical technicians David Denton and Karen Murphy use hot cell manipulators at Oak Ridge National Laboratory during the production of actinium-227. Radiochemical technicians David Denton and Karen Murphy use hot cell manipulators at Oak Ridge National Laboratory during the production of actinium-227.](/sites/default/files/styles/list_page_thumbnail/public/2016-P07827%5B1%5D.jpg?itok=yJbnFQLU)
The Department of Energy’s Oak Ridge National Laboratory is now producing actinium-227 (Ac-227) to meet projected demand for a highly effective cancer drug through a 10-year contract between the U.S. DOE Isotope Program and Bayer.
Scientists at Oak Ridge National Laboratory have conducted a series of breakthrough experimental and computational studies that cast doubt on a 40-year-old theory describing how polymers in plastic materials behave during processing.