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Frontier supercomputer

A multi-institutional team, led by a group of investigators at Oak Ridge National Laboratory, has been studying various SARS-CoV-2 protein targets, including the virus’s main protease. The feat has earned the team a finalist nomination for the Association of Computing Machinery, or ACM, Gordon Bell Special Prize for High Performance Computing-Based COVID-19 Research.

An organic solvent and water separate and form nanoclusters on the hydrophobic and hydrophilic sections of plant material, driving the efficient deconstruction of biomass. Credit: Michelle Lehman/ORNL, U.S. Dept. of Energy

Experiments led by researchers at ORNL have determined that several hepatitis C drugs can inhibit the SARS-CoV-2 main protease, a crucial protein enzyme that enables the novel coronavirus to reproduce.

coronavirus

NellOne Therapeutics has licensed a drug delivery system from the Department of Energy’s Oak Ridge National Laboratory that is designed to transport therapeutics directly to cells infected by SARS-CoV-2, the virus causing COVID-19.

stacked poplar logs

Popular wisdom holds tall, fast-growing trees are best for biomass, but new research by two U.S. Department of Energy national laboratories reveals that is only part of the equation.

An interactive visualization shows potential progression of BECCS to address carbon dioxide reduction goals. Credit: ORNL, U.S. Dept. of Energy

The combination of bioenergy with carbon capture and storage could cost-effectively sequester hundreds of millions of metric tons per year of carbon dioxide in the United States, making it a competitive solution for carbon management, according to a new analysis by ORNL scientists.

Hector J. Santos-Villalobos, left, and Oscar A. Martinez

Two staff members at the Department of Energy’s Oak Ridge National Laboratory have received prestigious HENAAC and Luminary Awards from Great Minds in STEM, a nonprofit organization that focuses on promoting STEM careers in underserved 

Andrew Harter, pictured, and fellow ORNL staff members formed Horizon31 to build a set of products and services that provide customized unmanned vehicle control systems. Credit: Carlos Jones/ORNL, U.S. Dept. of Energy

Horizon31, LLC has exclusively licensed a novel communication system that allows users to reliably operate unmanned vehicles such as drones from anywhere in the world using only an internet connection.

The hybrid inverter developed by ORNL is an intelligent power electronic inverter platform that can connect locally sited energy resources such as solar panels, energy storage and electric vehicles and interact efficiently with the utility power grid. Credit: Carlos Jones, ORNL/U.S. Dept of Energy.

ORNL researchers have developed an intelligent power electronic inverter platform that can connect locally sited energy resources such as solar panels, energy storage and electric vehicles and smoothly interact with the utility power grid.

Analyses of lung fluid cells from COVID-19 patients conducted on the nation’s fastest supercomputer point to gene expression patterns that may explain the runaway symptoms produced by the body’s response to SARS-CoV-2. Credit: Jason B. Smith/ORNL, U.S. Dept. of Energy

A team led by Dan Jacobson of Oak Ridge National Laboratory used the Summit supercomputer at ORNL to analyze genes from cells in the lung fluid of nine COVID-19 patients compared with 40 control patients.

The CrossVis application includes a parallel coordinates plot (left), a tiled image view (right) and other interactive data views. Credit: Chad Steed/Oak Ridge National Laboratory, U.S. Dept. of Energy

From materials science and earth system modeling to quantum information science and cybersecurity, experts in many fields run simulations and conduct experiments to collect the abundance of data necessary for scientific progress.