Skip to main content
Computational biophysicist Ada Sedova is using experiments and high-performance computing to explore the properties of biological systems and predict their form and function, including research to accelerate drug discovery for COVID-19. Photo credit: Jason Richards, Oak Ridge National Laboratory, U.S. Dept. of Energy.

Ada Sedova’s journey to Oak Ridge National Laboratory has taken her on the path from pre-med studies in college to an accelerated graduate career in mathematics and biophysics and now to the intersection of computational science and biology

The protease protein is both shaped like a heart and functions as one, allowing the virus replicate and spread. Inhibiting the protease would block virus reproduction. Credit: Andrey Kovalevsky/ORNL, U.S. Dept. of Energy

A team of researchers has performed the first room-temperature X-ray measurements on the SARS-CoV-2 main protease — the enzyme that enables the virus to reproduce.

From left, Peter Jiang, Elijah Martin and Benjamin Sulman have been selected for Early Career Research Program awards from the Department of Energy's Office of Science. Credit: Oak Ridge National Laboratory, U.S. Dept. of Energy

The Department of Energy’s Office of Science has selected three Oak Ridge National Laboratory scientists for Early Career Research Program awards.

ORNL researchers are leading virtual STEM outreach activities, such as an Internet of Things demonstration in which participants in ORCSGirls control an LED board remotely.

COVID-19 has upended nearly every aspect of our daily lives and forced us all to rethink how we can continue our work in a more physically isolated world.

Giri Prakash

Giri Prakash, data informatics scientist and director of the Department of Energy’s Atmospheric Radiation Measurement Data Center at Oak Ridge National Laboratory, has accepted an invitation from the National Academies of Sciences, Engineering, and Medicine to serve a four-year term on the U.S. National Committee for CODATA.

Recent research involving Oak Ridge National Laboratory’s Spallation Neutron Source demonstrates crystal-like heat conduction in a solid-liquid hybrid, AgCrSe2.

Research by an international team led by Duke University and the Department of Energy’s Oak Ridge National Laboratory scientists could speed the way to safer rechargeable batteries for consumer electronics such as laptops and cellphones.

Eriophorum vaginatum flourishes in the tundra biome

An international team of scientists found that rules governing plant growth hold true even at the edges of the world in the Arctic tundra.

Transformational Challenge Reactor Demonstration items

Researchers at the Department of Energy’s Oak Ridge National Laboratory are refining their design of a 3D-printed nuclear reactor core, scaling up the additive manufacturing process necessary to build it, and developing methods

Researchers at DOE’s Manufacturing Demonstration Facility at ORNL developed a reusable face mask prototype with injection molding that will enable industry to rapidly manufacture. Credit: Carlos Jones/Oak Ridge National Laboratory, U.S. Dept. of Energy

In the fight against the COVID-19 pandemic, it’s a race against the clock not only to find a vaccine but also to supply healthcare workers with life-saving equipment such as face shields, masks and test kits.

Coronavirus graphic

In the race to identify solutions to the COVID-19 pandemic, researchers at the Department of Energy’s Oak Ridge National Laboratory are joining the fight by applying expertise in computational science, advanced manufacturing, data science and neutron science.