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Media Contacts
![An ORNL-led team comprising researchers from multiple DOE national laboratories is using artificial intelligence and computational screening techniques – in combination with experimental validation – to identify and design five promising drug therapy approaches to target the SARS-CoV-2 virus. Credit: Michelle Lehman/ORNL, U.S. Dept. of Energy](/sites/default/files/styles/list_page_thumbnail/public/2021-06/frame1.png?h=d1cb525d&itok=51pwBWyP)
An ORNL-led team comprising researchers from multiple DOE national laboratories is using artificial intelligence and computational screening techniques – in combination with experimental validation – to identify and design five promising drug therapy approaches to target the SARS-CoV-2 virus.
![ORNL and NASA’s Jet Propulsion Laboratory scientists studied the formation of amorphous ice like the exotic ice found in interstellar space and on Jupiter’s moon, Europa. Credit: NASA/JPL-Caltech](/sites/default/files/styles/list_page_thumbnail/public/2021-06/EuropaClipper_Poster_08_2020_002_2__0.jpg?h=c6980913&itok=rS2sQda_)
Researchers from NASA’s Jet Propulsion Laboratory and Oak Ridge National Laboratory successfully created amorphous ice, similar to ice in interstellar space and on icy worlds in our solar system. They documented that its disordered atomic behavior is unlike any ice on Earth.
![The Department of Energy’s Office of Science has selected five Oak Ridge National Laboratory scientists for Early Career Research Program awards.](/sites/default/files/styles/list_page_thumbnail/public/2021-05/DOE%20ECRP%20winners_1.jpg?h=d1cb525d&itok=qW3-KeMF)
The Department of Energy’s Office of Science has selected five Oak Ridge National Laboratory scientists for Early Career Research Program awards.
![Neutron scattering experiments show electric charges, shown in red, blue and grey, in the SARS-CoV-2 main protease site where telaprevir binds to the structure. The experiments provide critical data for the design of small-molecule drugs to treat COVID-19. Credit: Jill Hemman and Michelle Lehman/ORNL, U.S. Dept. of Energy](/sites/default/files/styles/list_page_thumbnail/public/2021-03/after_transprent_background-wFill.png?h=c71d0c67&itok=jGFt_Ggj)
Scientists have found new, unexpected behaviors when SARS-CoV-2 – the virus that causes COVID-19 – encounters drugs known as inhibitors, which bind to certain components of the virus and block its ability to reproduce.
![The first neutron structure of the SARS-CoV-2 main protease enzyme revealed unexpected electrical charges in the amino acids cysteine (negative) and histidine (positive), providing key data about the virus’s replication. Credit: Jill Hemman/ORNL, U.S. Dept. of Energy](/sites/default/files/styles/list_page_thumbnail/public/2020-10/20-G01620_Protease_PR_proof2_0.jpg?h=3e3883a3&itok=XB_ZEDFQ)
To better understand how the novel coronavirus behaves and how it can be stopped, scientists have completed a three-dimensional map that reveals the location of every atom in an enzyme molecule critical to SARS-CoV-2 reproduction.
![A selfie from the Curiosity rover as it explores the surface of Mars. Like many spacecraft, Curiosity uses a radioisotope power system to help fuel its mission. Credit: NASA/JPL-Caltech/MSSS](/sites/default/files/styles/list_page_thumbnail/public/2020-09/Curiousity_1.jpg?h=86a9dded&itok=Jo0vD321)
Radioactive isotopes power some of NASA’s best-known spacecraft. But predicting how radiation emitted from these isotopes might affect nearby materials is tricky
![Hector J. Santos-Villalobos, left, and Oscar A. Martinez](/sites/default/files/styles/list_page_thumbnail/public/2020-08/henaac20.jpg?h=158d9140&itok=-NxooIrE)
Two staff members at the Department of Energy’s Oak Ridge National Laboratory have received prestigious HENAAC and Luminary Awards from Great Minds in STEM, a nonprofit organization that focuses on promoting STEM careers in underserved
![This photo shows the interior of the vessel of the General Atomics DIII-D National Fusion Facility in San Diego, where ORNL researchers are testing the suitability of tungsten to armor the inside of a fusion device. Credit: General Atomics](/sites/default/files/styles/list_page_thumbnail/public/2020-08/X2001140_Tungsten_DIIID_GeneralAtomics_Bumpus_jnj_0.jpg?h=fa422108&itok=9R1Nn6B_)
The inside of future nuclear fusion energy reactors will be among the harshest environments ever produced on Earth. What’s strong enough to protect the inside of a fusion reactor from plasma-produced heat fluxes akin to space shuttles reentering Earth’s atmosphere?
![Enzyme activity during organophosphate poisoning](/sites/default/files/styles/list_page_thumbnail/public/2020-08/anecdote1_0.png?h=d1cb525d&itok=wpYYilBI)
Pick your poison. It can be deadly for good reasons such as protecting crops from harmful insects or fighting parasite infection as medicine — or for evil as a weapon for bioterrorism. Or, in extremely diluted amounts, it can be used to enhance beauty.
![Pu-238 pellet drawing](/sites/default/files/styles/list_page_thumbnail/public/2020-07/Plutonium_Illustration_Blur.png?h=b6236d98&itok=wvSAbP64)
After its long journey to Mars beginning this summer, NASA’s Perseverance rover will be powered across the planet’s surface in part by plutonium produced at the Department of Energy’s Oak Ridge National Laboratory.