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Media Contacts
![Computational systems biologists at ORNL worked with the U.S. Department of Veterans Affairs and other institutions to identify 139 locations across the human genome tied to risk factors for varicose veins, marking a first step in the development of new treatments. Credit: Andy Sproles/ORNL, U.S. Dept. of Energy](/sites/default/files/styles/list_page_thumbnail/public/2023-01/vein06_0.jpg?h=d32448e0&itok=ItaGWCo5)
As part of a multi-institutional research project, scientists at ORNL leveraged their computational systems biology expertise and the largest, most diverse set of health data to date to explore the genetic basis of varicose veins.
![Researchers found that moderate levels of ash — sometimes found as spheres in biomass — do not significantly affect the mechanical properties of biocomposites made up of corn stover, switchgrass and PLA thermoplastic. Credit: Andy Sproles/ORNL, U.S. Dept. of Energy](/sites/default/files/styles/list_page_thumbnail/public/2022-12/sampleRecolor_v4_0.png?h=4d1c0665&itok=rRlgS-4C)
The presence of minerals called ash in plants makes little difference to the fitness of new naturally derived compound materials designed for additive manufacturing, an Oak Ridge National Laboratory-led team found.
![Technology to retrofit nonpowered dams such as the Lake Sequoyah Dam in North Carolina could be tested before deploying to ensure performance and reliability. Credit: Scott DeNeale/ORNL, U.S. Dept. of Energy](/sites/default/files/styles/list_page_thumbnail/public/2022-12/Sequoyah%20png.png?h=3873714b&itok=rYD7mUje)
Researchers at Oak Ridge National Laboratory have identified a key need for future hydropower innovations – full-scale testing – to better inform developers and operators before making major investments.
![ORNL researchers led by Michael Garvin, left, and David Kainer discovered genetic mutations called structural variants and linked them to autism spectrum disorders, demonstrating an approach that could be used to develop better diagnostics and drug therapies. Credit: Carlos Jones/ORNL, U.S. Dept. of Energy](/sites/default/files/styles/list_page_thumbnail/public/2022-11/Novstorytip_autism_0.png?h=707772c7&itok=6_DcjloQ)
ORNL researchers discovered genetic mutations that underlie autism using a new approach that could lead to better diagnostics and drug therapies.
![Conduit hydropower presents opportunities in every state. Credit: ORNL, U.S. Dept. of Energy](/sites/default/files/styles/list_page_thumbnail/public/2022-10/Picture1.png?h=3fe30658&itok=8NCUQOmV)
Millions of miles of pipelines and conduits across the United States make up an intricate network of waterways used for municipal, agricultural and industrial purposes.
![ORNL’s Tomás Rush explores the secret lives of fungi and plants for insights into the interactions that determine plant health. Credit: Genevieve Martin/ORNL, U.S. Dept. of Energy](/sites/default/files/styles/list_page_thumbnail/public/2022-10/Tomas%20Thumbnail.png?h=c6980913&itok=lhmIQFW4)
Tomás Rush began studying the mysteries of fungi in fifth grade and spent his college intern days tromping through forests, swamps and agricultural lands searching for signs of fungal plant pathogens causing disease on host plants.
![ORNL is studying how climate change may impact water availability for hydropower facilities such as the Shasta Dam and Lake in California. Credit: U.S. Bureau of Reclamation](/sites/default/files/styles/list_page_thumbnail/public/2022-09/Shasta%20Dam.png?h=2664774c&itok=F-QELlkQ)
ORNL has provided hydropower operators with new data to better prepare for extreme weather events and shifts in seasonal energy demands caused by climate change.
![Shown here is the structure of the NEMO protein. A team from ORNL conducted extensive molecular dynamics work on Summit by using both quantum mechanics and machine-learning methods to look at the binding affinity of NEMO and 3CLpro in humans and other species and to consider the structural models derived from the sequences of other coronaviruses. Image courtesy Nature Communications, Dan Jacobson/ORNL.](/sites/default/files/styles/list_page_thumbnail/public/2022-09/bradykinin_1.png?h=53873e96&itok=iBwJwFaV)
A new paper published in Nature Communications adds further evidence to the bradykinin storm theory of COVID-19’s viral pathogenesis — a theory that was posited two years ago by a team of researchers at the Department of Energy’s Oak Ridge National Laboratory.
![Solar panels funded by the Honnold Foundation are installed in Adjuntas, Puerto Rico. Credit: Fabio Andrade](/sites/default/files/styles/list_page_thumbnail/public/2022-09/grid-thumb2.jpg?h=252f27fa&itok=p9gjQHsR)
When Hurricane Maria battered Puerto Rico in 2017, winds snapped trees and destroyed homes, while heavy rains transformed streets into rivers. But after the storm passed, the human toll continued to grow as residents struggled without electricity for months. Five years later, power outages remain long and frequent.
![Technology Innovation Program](/sites/default/files/styles/list_page_thumbnail/public/2022-08/TIPbg_0.jpg?h=a50b7bdc&itok=_3vRlbkP)
Five technologies invented by scientists at the Department of Energy’s Oak Ridge National Laboratory have been selected for targeted investment through ORNL’s Technology Innovation Program.