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Media Contacts
![Illustration of the intricate organization of the PKA structure, wherein different parts of the protein are connected through elaborate hydrogen bonding networks (dashed yellow lines), glued together by the hydrophobic assemblies (light blue and orange volumes)—all working together to build the functional active site. Insert shows protonation of the transferred phosphoryl group (cyan mesh) and its many interactions with water and the active site amino acid residues. Credit: Jill Hemman/ORNL](/sites/default/files/styles/list_page_thumbnail/public/2019-03/19-G00204_MR_graphic_Kovalevsky_proof5_2.png?h=b7fbb1a9&itok=wrZFNX-o)
OAK RIDGE, Tenn., March 20, 2019—Direct observations of the structure and catalytic mechanism of a prototypical kinase enzyme—protein kinase A or PKA—will provide researchers and drug developers with significantly enhanced abilities to understand and treat fatal diseases and neurological disorders such as cancer, diabetes, and cystic fibrosis.
![Neutron scattering allowed direct observation of how aurein induces lateral segregation in the bacteria membranes, which creates instability in the membrane structure. This instability causes the membranes to fail, making harmful bacteria less effective.](/sites/default/files/styles/list_page_thumbnail/public/2019-03/Neutrons-FightingSuperbugs_0.jpg?h=e4b73f5a&itok=ebOQD-Mr)
As the rise of antibiotic-resistant bacteria known as superbugs threatens public health, Oak Ridge National Laboratory’s Shuo Qian and Veerendra Sharma from the Bhaba Atomic Research Centre in India are using neutron scattering to study how an antibacterial peptide interacts with and fights harmful bacteria.
Higher carbon dioxide levels caused 30 percent more wood growth in young forest stands across the temperate United States over a decade, according to an analysis led by Oak Ridge National Laboratory.
![ORNL will use state-of-the-art R&D tools at the Battery Manufacturing Facility to develop new methods for separating and reclaiming valuable materials from spent EV batteries.](/sites/default/files/styles/list_page_thumbnail/public/2019-02/2015-P01989cropped_1.jpg?h=f2976007&itok=mqNFUyYu)
The use of lithium-ion batteries has surged in recent years, starting with electronics and expanding into many applications, including the growing electric and hybrid vehicle industry. But the technologies to optimize recycling of these batteries have not kept pace.
![Using neutrons from the TOPAZ beamline, which is optimal for locating hydrogen atoms in materials, ORNL researchers observed a single-crystal neutron diffraction structure of the insoluble carbonate salt formed by absorption of carbon dioxide from the air.](/sites/default/files/styles/list_page_thumbnail/public/2019-02/Carbon_capture_neutrons_0.jpg?h=4137a28c&itok=ZBLNFjNc)
Researchers used neutron scattering at Oak Ridge National Laboratory’s Spallation Neutron Source to investigate the effectiveness of a novel crystallization method to capture carbon dioxide directly from the air.
![Researchers used machine learning methods on the ORNL Compute and Data Environment for Science, or CADES, to map vegetation communities in the Kougarok Watershed on the Seward Peninsula of Alaska. The colors denote different types of vegetation, such as w Researchers used machine learning methods on the ORNL Compute and Data Environment for Science, or CADES, to map vegetation communities in the Kougarok Watershed on the Seward Peninsula of Alaska. The colors denote different types of vegetation, such as w](/sites/default/files/styles/list_page_thumbnail/public/rs2019_highlight_plot_3d.png?itok=5bROV_ys)
A team of scientists led by Oak Ridge National Laboratory used machine learning methods to generate a high-resolution map of vegetation growing in the remote reaches of the Alaskan tundra.
![Researchers analyzed the oxygen structure (highlighted in red) found in a perovskite’s crystal structure at room temperature, 500°C and 900°C using neutron scattering at ORNL’s Spallation Neutron Source. Analyzing how these structures impact solid oxide f Researchers analyzed the oxygen structure (highlighted in red) found in a perovskite’s crystal structure at room temperature, 500°C and 900°C using neutron scattering at ORNL’s Spallation Neutron Source. Analyzing how these structures impact solid oxide f](/sites/default/files/styles/list_page_thumbnail/public/Neutron-Fueling_better_power_image1.jpg?itok=tZtIORnX)
A University of South Carolina research team is investigating the oxygen reduction performance of energy conversion materials called perovskites by using neutron diffraction at Oak Ridge National Laboratory’s Spallation Neutron Source.
![Nuclear—Deep space travel Nuclear—Deep space travel](/sites/default/files/styles/list_page_thumbnail/public/Screen%20Shot%202018-12-19%20at%2010.29.32%20AM.png?itok=hq0dlVIf)
By automating the production of neptunium oxide-aluminum pellets, Oak Ridge National Laboratory scientists have eliminated a key bottleneck when producing plutonium-238 used by NASA to fuel deep space exploration.
![Picture2.png Picture2.png](/sites/default/files/styles/list_page_thumbnail/public/Picture2_1.png?itok=IV4n9XEh)
Oak Ridge National Laboratory scientists studying fuel cells as a potential alternative to internal combustion engines used sophisticated electron microscopy to investigate the benefits of replacing high-cost platinum with a lower cost, carbon-nitrogen-manganese-based catalyst.
![18-G01703 PinchPoint-v2.jpg 18-G01703 PinchPoint-v2.jpg](/sites/default/files/styles/list_page_thumbnail/public/18-G01703%20PinchPoint-v2.jpg?itok=paJUPDI1)
Researchers used neutron scattering at Oak Ridge National Laboratory’s Spallation Neutron Source to investigate bizarre magnetic behavior, believed to be a possible quantum spin liquid rarely found in a three-dimensional material. QSLs are exotic states of matter where magnetism continues to fluctuate at low temperatures instead of “freezing” into aligned north and south poles as with traditional magnets.