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While studying the genes in poplar trees that control callus formation, scientists at Oak Ridge National Laboratory have uncovered genetic networks at the root of tumor formation in several human cancers.

Using as much as 50 percent lignin by weight, a new composite material created at ORNL is well suited for use in 3D printing.

Scientists at the Department of Energy’s Oak Ridge National Laboratory have created a recipe for a renewable 3D printing feedstock that could spur a profitable new use for an intractable biorefinery byproduct: lignin.

Omar Demerdash

Attracted to biology, math, and physics as a young student, Omar Demerdash decided that when the time came to narrow his academic interests he wouldn’t pick and choose: he’d pursue them all. Today he’s using his expertise in computational biophysics to model and analyze how molecules interact with p...

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For decades, biologists have believed a key enzyme in plants had one function—produce amino acids, which are vital to plant survival and also essential to human diets. But for Wellington Muchero, Meng Xie and their colleagues, this enzyme does more than advertised. They had run a series of experiments on poplar plants that consistently revealed mutations in a structure of the life-sustaining enzyme that was not previously known to exist.

Esther Parish

Esther Parish’s holistic approach to life is apparent not only in her environmental research at Oak Ridge National Laboratory, but in her careful cultivation of a future crop of young scientists. Her expertise as a geographer coupled with a keen interest in the natural world drives Parish’s resea...

Oak Ridge National Laboratory bioinformatics researcher Dan Jacobson plugs AI, deep learning into biosystems.

Dan Jacobson is illuminating the workings of biological systems from the molecular scale up by leveraging Oak Ridge National Laboratory’s supercomputing resources to create machine- and deep-learning techniques more easily understood by humans

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A new process to identify certain microbes in women could be used to diagnose endometriosis without invasive surgery, even before symptoms start. A collaborative research team including Oak Ridge National Laboratory analyzed bacteria from a small sample of premenopausal women undergoing laparoscopic surgery for suspected endometriosis.
David Weston

David Weston became fascinated with plant genetics and ecology in college, and now with the support provided by the DOE Office of Science Early Career Research Program, he will link those fields as he studies plant-microbe symbiosis. The research will focus on sphagnum moss, a dominant plant of n...

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Working backwards has moved Josh Michener’s research far forward as he uses evolution and genetics to engineer microbes for better conversion of plants into biofuels and biochemicals. In his work for the BioEnergy Science Center at ORNL, for instance, “we’ve gotten good at engineering microbes th...