Robert Hettich: Decoding biological complexity with next-gen mass spectrometry
The probe of an atomic force microscope (AFM) scans a surface to reveal details at a resolution 1,000 times greater than that of an optical microscope. That makes AFM the premier tool for analyzing physical features, but it cannot tell scientists anything about chemistry. For that they turn to the mass spectrometer (MS).
With more than 30 patents, James Klett is no stranger to success, but perhaps the Oak Ridge National Laboratory researcher’s most noteworthy achievement didn’t start out so hot – or so it seemed at the time.
From the bluebird painting propped against her office wall and the deer she mentions seeing outside her office window, Linda Lewis might be mistaken for a wildlife biologist at first glance. But rather than trailing animal tracks, Lewis, a researcher at the Department of Energy’s Oak Ridge National Laboratory, is more interested in marks left behind by humans.
Graphene, a strong, lightweight carbon honeycombed structure that’s only one atom thick, holds great promise for energy research and development. Recently scientists with the Fluid Interface Reactions, Structures, and Transport (FIRST) Energy Frontier Research Center (EFRC), led by the US Department of Energy’s Oak Ridge National Laboratory, revealed graphene can serve as a proton-selective permeable membrane, providing a new basis for streamlined and more efficient energy technologies such as improved fuel cells.
Andrew Stack, a geochemist at the Department of Energy’s Oak Ridge National Laboratory, advances understanding of the dynamics of minerals underground.
Throw a rock through a window made of silica glass, and the brittle, insulating oxide pane shatters. But whack a golf ball with a club made of metallic glass—a resilient conductor that looks like metal—and the glass not only stays intact but also may drive the ball farther than conventional clubs. In light of this contrast, the nature of glass seems anything but clear.
In 2015, American consumers will finally be able to purchase fuel cell cars from Toyota and other manufacturers. Although touted as zero-emissions vehicles, most of the cars will run on hydrogen made from natural gas, a fossil fuel that contributes to global warming.
If such a designation existed, Nazanin Bassiri-Gharb would be on the fast track to becoming an Oak Ridge National Laboratory “super user.” Her research on nanoscale materials has taken her all across the ORNL campus, from scanning probe and electron microscopes at the Center for Nanophase Materials Sciences to neutron reflectometry at the Spallation Neutron Source and radiation equipment in the Materials Science and Technology Division.
Old thinking was that gold, while good for jewelry, was not of much use for chemists because it is relatively nonreactive. That changed a decade ago when scientists hit a rich vein of discoveries revealing that this noble metal, when structured into nanometer-sized particles, can speed up chemical reactions important in mitigating environmental pollutants and producing hard-to-make specialty chemicals.
A simple new technique to form interlocking beads of water in ambient conditions could prove valuable for applications in biological sensing, membrane research and harvesting water from fog.