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Media Contacts
![An ORNL-led team comprising researchers from multiple DOE national laboratories is using artificial intelligence and computational screening techniques – in combination with experimental validation – to identify and design five promising drug therapy approaches to target the SARS-CoV-2 virus. Credit: Michelle Lehman/ORNL, U.S. Dept. of Energy](/sites/default/files/styles/list_page_thumbnail/public/2021-06/frame1.png?h=d1cb525d&itok=51pwBWyP)
An ORNL-led team comprising researchers from multiple DOE national laboratories is using artificial intelligence and computational screening techniques – in combination with experimental validation – to identify and design five promising drug therapy approaches to target the SARS-CoV-2 virus.
![Aviation contributes about 2.5% of global carbon dioxide emissions. To greatly reduce its emissions, the U.S. commercial aviation sector needs new methods of making sustainable aviation fuel. Credit: Ross Parmly/Unsplash](/sites/default/files/styles/list_page_thumbnail/public/2021-06/ross-parmly-rf6ywHVkrlY-unsplash_0.jpg?h=fee4874d&itok=BEdQYEQ2)
ORNL’s Zhenglong Li led a team tasked with improving the current technique for converting ethanol to C3+ olefins and demonstrated a unique composite catalyst that upends current practice and drives down costs. The research was published in ACS Catalysis.
![A research team led by ORNL’s Xiaohan Yang used a gene from agave to engineer higher yield, improved stress tolerance and greater carbon sequestration in tobacco plants. Credit: Carlos Jones/ORNL, U.S. Dept. of Energy](/sites/default/files/styles/list_page_thumbnail/public/2021-06/2019-P09831.jpg?h=39b94f55&itok=8O8d7xMb)
Scientists at ORNL have discovered a single gene that simultaneously boosts plant growth and tolerance for stresses such as drought and salt, all while tackling the root cause of climate change by enabling plants to pull more carbon dioxide from the atmosphere.
![Scientists genetically engineered bacteria for itaconic acid production, creating dynamic controls that separate microbial growth and production phases for increased efficiency and acid yield. Credit: NREL](/sites/default/files/styles/list_page_thumbnail/public/2021-05/Putida_forAdam_2clr_2.jpg?h=71f44bf2&itok=8u0ZVufx)
A research team led by Oak Ridge National Laboratory bioengineered a microbe to efficiently turn waste into itaconic acid, an industrial chemical used in plastics and paints.
![Belinda Akpa applies her diverse expertise and high-performance computing to accelerate the drug discovery process and increase the chances of success when candidate molecules go to clinical trials. Credit: Carlos Jones/ORNL, U.S. Dept. of Energy](/sites/default/files/styles/list_page_thumbnail/public/2021-04/2021-P02772_1.jpg?h=0a8b6f8b&itok=seLu5znj)
Belinda Akpa is a chemical engineer with a talent for tackling big challenges and fostering inclusivity and diversity in the next generation of scientists.
![ORNL ecosystem scientist Colleen Iversen talked to fourth-grade students at Coulter Grove Intermediate School in Maryville on Friday, April 23, as part of National Environmental Education Week.](/sites/default/files/styles/list_page_thumbnail/public/2021-04/Sciencetalk3_1.jpg?h=29234840&itok=wWaAJG05)
Esther Parish is one of eight scientists from the Department of Energy's Oak Ridge National Laboratory talking to students in nine schools across East Tennessee as part of National Environmental Education Week, or EE Week.
![Rich Giannone uses bioanalytical mass spectrometry to examine proteins, the primary driver in biological systems.](/sites/default/files/styles/list_page_thumbnail/public/2021-04/2021-P02194_small.jpg?h=c6980913&itok=bc6MRBX6)
Rich Giannone uses bioanalytical mass spectrometry to examine proteins, the primary driver in biological systems.
![ATOM logo](/sites/default/files/styles/list_page_thumbnail/public/2021-03/ATOM_Logo_small.png?h=8f9cfe54&itok=Qpezfk8V)
The Accelerating Therapeutics for Opportunities in Medicine , or ATOM, consortium today announced the U.S. Department of Energy’s Oak Ridge, Argonne and Brookhaven national laboratories are joining the consortium to further develop ATOM’s artificial intelligence, or AI-driven, drug discovery platform.
![Targeted alpha therapy can deliver radiation to specific cells, with minimal effect on surrounding, healthy cells. Credit: Michelle Lehman and Jaimee Janiga/ORNL, U.S. Dept. of Energy](/sites/default/files/styles/list_page_thumbnail/public/2021-03/gif_high_res.gif?h=ae1281eb&itok=QtNBjm3O)
A rare isotope in high demand for treating cancer is now more available to pharmaceutical companies developing and testing new drugs.
![Neutron scattering experiments show electric charges, shown in red, blue and grey, in the SARS-CoV-2 main protease site where telaprevir binds to the structure. The experiments provide critical data for the design of small-molecule drugs to treat COVID-19. Credit: Jill Hemman and Michelle Lehman/ORNL, U.S. Dept. of Energy](/sites/default/files/styles/list_page_thumbnail/public/2021-03/after_transprent_background-wFill.png?h=c71d0c67&itok=jGFt_Ggj)
Scientists have found new, unexpected behaviors when SARS-CoV-2 – the virus that causes COVID-19 – encounters drugs known as inhibitors, which bind to certain components of the virus and block its ability to reproduce.