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Media Contacts
![Shown here is the structure of the NEMO protein. A team from ORNL conducted extensive molecular dynamics work on Summit by using both quantum mechanics and machine-learning methods to look at the binding affinity of NEMO and 3CLpro in humans and other species and to consider the structural models derived from the sequences of other coronaviruses. Image courtesy Nature Communications, Dan Jacobson/ORNL.](/sites/default/files/styles/list_page_thumbnail/public/2022-09/bradykinin_1.png?h=53873e96&itok=iBwJwFaV)
A new paper published in Nature Communications adds further evidence to the bradykinin storm theory of COVID-19’s viral pathogenesis — a theory that was posited two years ago by a team of researchers at the Department of Energy’s Oak Ridge National Laboratory.
![A team of researchers used mathematics to predict which areas of the SARS-CoV-2 spike protein are most likely to mutate. Credit: Jill Hemman/ORNL, U.S. Dept. of Energy](/sites/default/files/styles/list_page_thumbnail/public/2022-09/covid19_jh_0_0.png?h=252f27fa&itok=c3Qts7j0)
Researchers from ORNL, the University of Tennessee at Chattanooga and Tuskegee University used mathematics to predict which areas of the SARS-CoV-2 spike protein are most likely to mutate.
![Technology Innovation Program](/sites/default/files/styles/list_page_thumbnail/public/2022-08/TIPbg_0.jpg?h=a50b7bdc&itok=_3vRlbkP)
Five technologies invented by scientists at the Department of Energy’s Oak Ridge National Laboratory have been selected for targeted investment through ORNL’s Technology Innovation Program.
![Data from different sources are joined on platforms created by ORNL researchers to offer better information for decision makers. Credit: ORNL/Nathan Armistead](/sites/default/files/styles/list_page_thumbnail/public/2022-07/COVID%20dashboards%20story%20graphic_0.jpg?h=d1cb525d&itok=ubNOO2W4)
When the COVID-19 pandemic stunned the world in 2020, researchers at ORNL wondered how they could extend their support and help
![ORNL polymer scientists Tomonori Saito, left, and Sungjin Kim upcycled waste plastic to create a stronger, tougher, solvent-resistant material for new additive manufacturing applications. Credit: Genevieve Martin/ORNL, U.S. Dept. of Energy](/sites/default/files/styles/list_page_thumbnail/public/2022-06/2022-P04745_2.jpg?h=c6980913&itok=9DI9K-vJ)
ORNL researchers have developed an upcycling approach that adds value to discarded plastics for reuse in additive manufacturing, or 3D printing.
![Frontier has arrived, and ORNL is preparing for science on Day One. Credit: Carlos Jones/ORNL, Dept. of Energy](/sites/default/files/styles/list_page_thumbnail/public/2022-05/Frontier%20endcap.jpg?h=c6980913&itok=5i5DUzQz)
The Frontier supercomputer at the Department of Energy’s Oak Ridge National Laboratory earned the top ranking today as the world’s fastest on the 59th TOP500 list, with 1.1 exaflops of performance. The system is the first to achieve an unprecedented level of computing performance known as exascale, a threshold of a quintillion calculations per second.
![Logan Sturm, Alvin M. Weinberg Fellow at ORNL, creates a mashup between additive manufacturing and cybersecurity research. Credit: Carlos Jones/ORNL, U.S. Dept. of Energy](/sites/default/files/styles/list_page_thumbnail/public/2022-05/sturm-lab.jpg?h=1de2f7a8&itok=nYiuVTGx)
How an Alvin M. Weinberg Fellow is increasing security for critical infrastructure components
![Oak Ridge National Laboratory researchers quantified human behaviors during the early days of COVID-19, which could be useful for disaster response or city planning. Credit: Nathan Armistead/ORNL, U.S. Dept. of Energy](/sites/default/files/styles/list_page_thumbnail/public/2022-05/COVID%20human%20behavior_0.jpg?h=9fc2b970&itok=E7nSPBpk)
Researchers at Oak Ridge National Laboratory have empirically quantified the shifts in routine daytime activities, such as getting a morning coffee or takeaway dinner, following safer at home orders during the early days of the COVID-19 pandemic.
![Physicist Charles Havener uses the NASA end station at ORNL’s Multicharged Ion Research Facility to simulate the origin of X-ray emissions from space. Credit: Carlos Jones/ORNL, U.S. Dept. of Energy](/sites/default/files/styles/list_page_thumbnail/public/2022-05/2021-P08920_0.jpg?h=c6980913&itok=zfXx31gD)
Scientists are using Oak Ridge National Laboratory’s Multicharged Ion Research Facility to simulate the cosmic origin of X-ray emissions resulting when highly charged ions collide with neutral atoms and molecules, such as helium and gaseous hydrogen.
![With seismic and acoustic data recorded by remote sensors near ORNL’s High Flux Isotope Reactor, researchers could predict whether the reactor was on or off with 98% accuracy. Credit: Nathan Armistead/ORNL, U.S. Dept. of Energy](/sites/default/files/styles/list_page_thumbnail/public/2022-05/Seismo%20acoustic%20draft%20v3_0.jpg?h=2e111cc1&itok=0oLpYDc8)
An Oak Ridge National Laboratory team developed a novel technique using sensors to monitor seismic and acoustic activity and machine learning to differentiate operational activities at facilities from “noise” in the recorded data.