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![ORNL scientists developed a method that improves the accuracy of the CRISPR Cas9 gene editing tool used to modify microbes for renewable fuels and chemicals production. This research draws on the lab’s expertise in quantum biology, artificial intelligence and synthetic biology. Credit: Philip Gray/ORNL, U.S. Dept. of Energy](/sites/default/files/styles/list_page_thumbnail/public/2023-11/CRISPR%20Quantum%20AI_2_23-G07105-DOE-BER-BESSD-comms-graphic-pcg_2.jpg?h=847b7ff0&itok=WD2dBsAC)
Scientists at ORNL used their expertise in quantum biology, artificial intelligence and bioengineering to improve how CRISPR Cas9 genome editing tools work on organisms like microbes that can be modified to produce renewable fuels and chemicals.
![Two hybrid poplar plants, middle and right, engineered with the PtrXB38 hub gene exhibited a drastic increase in root and callus formation compared with a wild-type control plant, left. Credit: Tao Yao/ORNL, U.S. Dept. of Energy](/sites/default/files/styles/list_page_thumbnail/public/2023-10/Poplar%20root%20story%20tip%20as%20JPEG_0.jpg?h=7bc542ef&itok=HNxpeEt6)
Oak Ridge National Laboratory scientists identified a gene “hotspot” in the poplar tree that triggers dramatically increased root growth. The discovery supports development of better bioenergy crops and other plants that can thrive in difficult conditions while storing more carbon belowground.
![The sun sets behind the ORNL Visitor Center in this aerial photo from April 2023. Credit: Kase Clapp/ORNL, U.S. Dept. of Energy](/sites/default/files/styles/list_page_thumbnail/public/2023-10/sunset_visitor-center_0.png?h=10d202d3&itok=jLImPT0R)
In fiscal year 2023 — Oct. 1–Sept. 30, 2023 — Oak Ridge National Laboratory was awarded more than $8 million in technology maturation funding through the Department of Energy’s Technology Commercialization Fund, or TCF.
![When exposed to radiation, electrons produced within molten zinc chloride, or ZnCl2, can be observed in three distinct singly occupied molecular orbital states, plus a more diffuse, delocalized state. Credit: Hung H. Nguyen/University of Iowa](/sites/default/files/styles/list_page_thumbnail/public/2023-10/bernard-wide_0.png?h=dba5e3ef&itok=DgnYZ_Vy)
In a finding that helps elucidate how molten salts in advanced nuclear reactors might behave, scientists have shown how electrons interacting with the ions of the molten salt can form three states with different properties. Understanding these states can help predict the impact of radiation on the performance of salt-fueled reactors.
![: This schematic of tokamak core-pedestal-boundary regions show what will be simulated by an ORNL project applying machine learning to plasma physics modeling. Credit: Giacomin et al., J. Comput. Phys., 463, (2022) 111294, https://doi.org/10.1016/j.jcp.2022.11294](/sites/default/files/styles/list_page_thumbnail/public/2023-10/Fusion%20tokamak%20simulator.png?h=e1e3aba4&itok=kiVnri5A)
ORNL will lead three new DOE-funded projects designed to bring fusion energy to the grid on a rapid timescale.
![A group of ORNL staff standing in a long corridor with flags hanging from the ceiling](/sites/default/files/styles/list_page_thumbnail/public/2023-09/2023-P08315_0.jpg?h=036a71b7&itok=R3n9ZYXT)
For 25 years, scientists at Oak Ridge National Laboratory have used their broad expertise in human health risk assessment, ecology, radiation protection, toxicology and information management to develop widely used tools and data for the U.S. Environmental Protection Agency as part of the agency’s Superfund program.
![Xiaohan Yang is using his expertise in synthetic biology and capabilities like the Advanced Plant Phenotyping Laboratory at Oak Ridge National Laboratory to accelerate the development of drought-tolerant, fast-growing bioenergy crops suited for conversion into clean jet fuels. Credit: Genevieve Martin/ORNL, U.S. Dept. of Energy](/sites/default/files/styles/list_page_thumbnail/public/2023-09/XiaohanYangGreenhouse_2023-P03109_0.jpg?h=c6980913&itok=MCyYhyrO)
Scientist Xiaohan Yang’s research at the Department of Energy’s Oak Ridge National Laboratory focuses on transforming plants to make them better sources of renewable energy and carbon storage.
![Scientists conducted microbial DNA sampling at a Yellowstone National Park hot spring for a study sponsored by DOE’s Biological and Environmental Research program, the National Science Foundation and NASA. Credit: Mircea Podar/ORNL, U.S. Dept. of Energy](/sites/default/files/styles/list_page_thumbnail/public/2023-09/hot-springs_0.png?h=e68b456d&itok=ioNfSScN)
Oak Ridge National Laboratory scientists studied hot springs on different continents and found similarities in how some microbes adapted despite their geographic diversity.
![ORNL researchers are demonstrating an automation system for this portable system, currently based in Colorado, for treatment of non-traditional water sources to drinking water standards. Credit: Tzahi Cath/Colorado School of Mines](/sites/default/files/styles/list_page_thumbnail/public/2023-09/NAWI_comp01_0.jpg?h=d1cb525d&itok=I2fCHpSN)
Researchers at ORNL are developing advanced automation techniques for desalination and water treatment plants, enabling them to save energy while providing affordable drinking water to small, parched communities without high-quality water supplies.
![Mirko Musa was always fascinated by the power of rivers, specifically how these mighty waterways sculpt landscapes. Now, as a water power researcher, he’s finding ways to harness that power and protect rivers at the same time. Credit: Carlos Jones/ORNL, U.S. Dept. of Energy](/sites/default/files/styles/list_page_thumbnail/public/2023-08/mirkomusa_2023-p05038.jpg?h=c6980913&itok=3Az47BKS)
Mirko Musa spent his childhood zigzagging his bike along the Po River. The Po, Italy’s longest river, cuts through a lush valley of grain and vegetable fields, which look like a green and gold ocean spreading out from the river’s banks.