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Promethium’s secrets exposed
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Molecular dynamics simulations of the Fs-peptide revealed the presence of at least eight distinct intermediate stages during the process of protein folding. The image depicts a fully folded helix (1), various transitional forms (2–8), and one misfolded state (9). By studying these protein folding pathways, scientists hope to identify underlying factors that affect human health.

Modified deep-learning algorithms unveil features of shape-shifting proteins

Using artificial neural networks designed to emulate the inner workings of the human brain, deep-learning algorithms deftly peruse and analyze large quantities of data. Applying this technique to science problems can help unearth historically elusive solutions.

(From left) ORNL Associate Laboratory Director for Computing and Computational Sciences Jeff Nichols; ORNL Health Data Sciences Institute Director Gina Tourassi; DOE Deputy Under Secretary for Science Thomas Cubbage; ORNL Task Lead for Biostatistics Blair Christian; and ORNL Research Scientist Ioana Danciu were invited to the White House to showcase an ORNL-developed digital tool aimed at better matching cancer patients with clinical trials.

New ORNL AI tool revolutionizes process for matching cancer patients with clinical trials

OAK RIDGE, Tenn., March 4, 2019—A team of researchers from the Department of Energy’s Oak Ridge National Laboratory Health Data Sciences Institute have harnessed the power of artificial intelligence to better match cancer patients with clinical trials.

carbon nanospikes

ReactWell licenses ORNL catalyst for energy conversion applications

OAK RIDGE, Tenn., March 1, 2019—ReactWell, LLC, has licensed a novel waste-to-fuel technology from the Department of Energy’s Oak Ridge National Laboratory to improve energy conversion methods for cleaner, more efficient oil and gas, chemical and

ORNL scientists used commuting behavior data from East Tennessee to demonstrate how machine learning models can easily accept new data, quickly re-train themselves and update predictions about commuting patterns. Credit: April Morton/Oak Ridge National La

Commuting—Oh, the places you’ll go

Oak Ridge National Laboratory geospatial scientists who study the movement of people are using advanced machine learning methods to better predict home-to-work commuting patterns.

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Tree of life: Poplar studies yield human cancer insights

While studying the genes in poplar trees that control callus formation, scientists at Oak Ridge National Laboratory have uncovered genetic networks at the root of tumor formation in several human cancers.

Using as much as 50 percent lignin by weight, a new composite material created at ORNL is well suited for use in 3D printing.

New composite advances lignin as a renewable 3D printing material

Scientists at the Department of Energy’s Oak Ridge National Laboratory have created a recipe for a renewable 3D printing feedstock that could spur a profitable new use for an intractable biorefinery byproduct: lignin.

From left, Amit Naskar, Ngoc Nguyen and Christopher Bowland in ORNL’s Carbon and Composites Group bring a new capability—structural health monitoring—to strong, lightweight materials promising for transportation applications.

Self-sensing materials are here

Carbon fiber composites—lightweight and strong—are great structural materials for automobiles, aircraft and other transportation vehicles. They consist of a polymer matrix, such as epoxy, into which reinforcing carbon fibers have been embedded. Because of differences in the mecha...

Infected Poplar

Genetic behavior reveals cause of death in poplars essential to ecosystems, industry

Scientists studying a valuable, but vulnerable, species of poplar have identified the genetic mechanism responsible for the species’ inability to resist a pervasive and deadly disease. Their finding, published in the Proceedings of the National Academy of Sciences, could lead to more successful hybrid poplar varieties for increased biofuels and forestry production and protect native trees against infection.

Composites scientist and engineer Vlastimil Kunc with the latest large-scale 3Dprinter at the MDF.

Vlastimil Kunc: Setting sail in the world of composites

Vlastimil Kunc grew up in a family of scientists where his natural curiosity was encouraged—an experience that continues to drive his research today in polymer composite additive manufacturing at Oak Ridge National Laboratory. “I’ve been interested in the science of composites si...

ORNL’s Steven Young (left) and Travis Johnston used Titan to prove the design and training of deep learning networks could be greatly accelerated with a capable computing system.

ORNL researchers use Titan to accelerate design, training of deep learning networks

A team of researchers from the Department of Energy’s Oak Ridge National Laboratory has married artificial intelligence and high-performance computing to achieve a peak speed of 20 petaflops in the generation and training of deep learning networks on the