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Coronavirus research

Researchers at the Department of Energy’s Oak Ridge National Laboratory have used Summit, the world’s most powerful and smartest supercomputer, to identify 77 small-molecule drug compounds that might warrant further study in the fight

Scientists created a novel polymer that is as effective as natural proteins in transporting protons through a membrane. Credit: ORNL/Jill Hemman

Biological membranes, such as the “walls” of most types of living cells, primarily consist of a double layer of lipids, or “lipid bilayer,” that forms the structure, and a variety of embedded and attached proteins with highly specialized functions, including proteins that rapidly and selectively transport ions and molecules in and out of the cell.

The image visualizes how the team’s multitask convolutional neural network classifies primary cancer sites. Image credit: Hong-Jun Yoon/ORNL

As the second-leading cause of death in the United States, cancer is a public health crisis that afflicts nearly one in two people during their lifetime.

ORNL’s collaboration with Cincinati Children’s Hospital Medical Center will leverage the lab’s expertise in high-performance computing and safe, secure recordkeeping. Credit: Genevieve Martin/Oak Ridge National Laboratory, U.S. Dept. of Energy

Oak Ridge National Laboratory will partner with Cincinnati Children’s Hospital Medical Center to explore ways to deploy expertise in health data science that could more quickly identify patients’ mental health risk factors and aid in

Liane Russell

A select group gathered on the morning of Dec. 20 at the Department of Energy’s Oak Ridge National Laboratory for a symposium in honor of Liane B. Russell, the renowned ORNL mammalian geneticist who died in July.

Costas Tsouris portrait

While Tsouris’ water research is diverse in scope, its fundamentals are based on basic science principles that remain largely unchanged, particularly in a mature field like chemical engineering.

Water and energy are inextricably linked, yet in our 20th-century water systems we use freshwater once then throw it away. With innovations designed to enhance desalination technologies, agricultural runoff, produced water from industry, and inland brackish groundwater that are now seen as untreatable could all be sources of clean, safe, and affordable water.

The National Alliance for Water Innovation, a partnership of the Department of Energy’s Oak Ridge National Laboratory, other national labs, university and private sector partners, has been awarded a five-year, $100 million Energy-Water Desalination Hub by DOE to address water security issues in the United States.

A new method uses E. coli to generate DNA with methylation patterns that target microbes recognize and accept as their own, facilitating customization of microbes for biofuels production.

Scientists at the US Department of Energy’s Oak Ridge National Laboratory have demonstrated a method to insert genes into a variety of microorganisms that previously would not accept foreign DNA, with the goal of creating custom microbes to break down plants for bioenergy.

Desalination process

A new method developed at Oak Ridge National Laboratory improves the energy efficiency of a desalination process known as solar-thermal evaporation. 

ORNL collaborator Hsiu-Wen Wang led the neutron scattering experiments at the Spallation Neutron Source to probe complex electrolyte solutions that challenge nuclear waste processing at Hanford and other sites. Credit: Genevieve Martin/Oak Ridge National Laboratory, U.S. Dept. of Energy.

Researchers at the Department of Energy’s Oak Ridge National Laboratory, Pacific Northwest National Laboratory and Washington State University teamed up to investigate the complex dynamics of low-water liquids that challenge nuclear waste processing at federal cleanup sites.