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Media Contacts
![Illustration of the intricate organization of the PKA structure, wherein different parts of the protein are connected through elaborate hydrogen bonding networks (dashed yellow lines), glued together by the hydrophobic assemblies (light blue and orange volumes)—all working together to build the functional active site. Insert shows protonation of the transferred phosphoryl group (cyan mesh) and its many interactions with water and the active site amino acid residues. Credit: Jill Hemman/ORNL](/sites/default/files/styles/list_page_thumbnail/public/2019-03/19-G00204_MR_graphic_Kovalevsky_proof5_2.png?h=b7fbb1a9&itok=wrZFNX-o)
OAK RIDGE, Tenn., March 20, 2019—Direct observations of the structure and catalytic mechanism of a prototypical kinase enzyme—protein kinase A or PKA—will provide researchers and drug developers with significantly enhanced abilities to understand and treat fatal diseases and neurological disorders such as cancer, diabetes, and cystic fibrosis.
![Neutron scattering allowed direct observation of how aurein induces lateral segregation in the bacteria membranes, which creates instability in the membrane structure. This instability causes the membranes to fail, making harmful bacteria less effective.](/sites/default/files/styles/list_page_thumbnail/public/2019-03/Neutrons-FightingSuperbugs_0.jpg?h=e4b73f5a&itok=ebOQD-Mr)
As the rise of antibiotic-resistant bacteria known as superbugs threatens public health, Oak Ridge National Laboratory’s Shuo Qian and Veerendra Sharma from the Bhaba Atomic Research Centre in India are using neutron scattering to study how an antibacterial peptide interacts with and fights harmful bacteria.
![In this MXene electrode, choosing the appropriate solvent for the electrolyte can increase energy density significantly. This scanning electron microscopy image shows fine features of a film only 5 microns thick—approximately 10 times narrower than a human hair. Credit: Drexel University; image by Tyler Mathis](/sites/default/files/styles/list_page_thumbnail/public/2019-03/MXene%20electrode_0.jpg?h=e9daaebf&itok=YNpINGl2)
![(From left) ORNL Associate Laboratory Director for Computing and Computational Sciences Jeff Nichols; ORNL Health Data Sciences Institute Director Gina Tourassi; DOE Deputy Under Secretary for Science Thomas Cubbage; ORNL Task Lead for Biostatistics Blair Christian; and ORNL Research Scientist Ioana Danciu were invited to the White House to showcase an ORNL-developed digital tool aimed at better matching cancer patients with clinical trials.](/sites/default/files/styles/list_page_thumbnail/public/2019-03/TourassiWH%5B1%5D.png?h=26b5064d&itok=HUC2iYmE)
OAK RIDGE, Tenn., March 4, 2019—A team of researchers from the Department of Energy’s Oak Ridge National Laboratory Health Data Sciences Institute have harnessed the power of artificial intelligence to better match cancer patients with clinical trials.
![carbon nanospikes carbon nanospikes](/sites/default/files/styles/list_page_thumbnail/public/carbon_nanospikes.jpg?itok=D0GNAvH4)
OAK RIDGE, Tenn., March 1, 2019—ReactWell, LLC, has licensed a novel waste-to-fuel technology from the Department of Energy’s Oak Ridge National Laboratory to improve energy conversion methods for cleaner, more efficient oil and gas, chemical and
![To develop complex materials with superior properties, Vera Bocharova uses diverse methods including broadband dielectric spectroscopy. Credit: Oak Ridge National Laboratory, U.S. Dept. of Energy; photographer Jason Richards](/sites/default/files/styles/list_page_thumbnail/public/2019-02/2016-p05202.jpg?h=b6236d98&itok=w-Sd8giq)
Vera Bocharova at the Department of Energy’s Oak Ridge National Laboratory investigates the structure and dynamics of soft materials—polymer nanocomposites, polymer electrolytes and biological macromolecules—to advance materials and technologies for energy, medicine and other applications.
![An ORNL-developed graphite foam, which could be used in plasma-facing components in fusion reactors, performed well during testing at the Wendlestein 7-X stellarator in Germany.](/sites/default/files/styles/list_page_thumbnail/public/2019-02/W7-XPlasmaExposure_0.jpg?h=d5d04e3b&itok=uKiauhdF)
Scientists have tested a novel heat-shielding graphite foam, originally created at Oak Ridge National Laboratory, at Germany’s Wendelstein 7-X stellarator with promising results for use in plasma-facing components of fusion reactors.
![Sean Hearne has been named director of the Center for Nanophase Materials Sciences at Oak Ridge National Laboratory. Sean Hearne has been named director of the Center for Nanophase Materials Sciences at Oak Ridge National Laboratory.](/sites/default/files/styles/list_page_thumbnail/public/news/images/2019-P00370.jpg?itok=6sC8Bnj7)
OAK RIDGE, Tenn., Feb. 8, 2019—The Department of Energy’s Oak Ridge National Laboratory has named Sean Hearne director of the Center for Nanophase Materials Sciences. The center is a DOE Office of Science User Facility that brings world-leading resources and capabilities to the nanoscience resear...
![Coexpression_hi-res_image[1].jpg Coexpression_hi-res_image[1].jpg](/sites/default/files/styles/list_page_thumbnail/public/Coexpression_hi-res_image%5B1%5D_0.jpg?itok=OnLe-krT)
While studying the genes in poplar trees that control callus formation, scientists at Oak Ridge National Laboratory have uncovered genetic networks at the root of tumor formation in several human cancers.
![ORNL alanine_graphic.jpg ORNL alanine_graphic.jpg](/sites/default/files/styles/list_page_thumbnail/public/ORNL%20alanine_graphic.jpg?itok=iRLfcOw-)
OAK RIDGE, Tenn., Jan. 31, 2019—A new electron microscopy technique that detects the subtle changes in the weight of proteins at the nanoscale—while keeping the sample intact—could open a new pathway for deeper, more comprehensive studies of the basic building blocks of life.