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Belinda Akpa applies her diverse expertise and high-performance computing to accelerate the drug discovery process and increase the chances of success when candidate molecules go to clinical trials. Credit: Carlos Jones/ORNL, U.S. Dept. of Energy

Belinda Akpa is a chemical engineer with a talent for tackling big challenges and fostering inclusivity and diversity in the next generation of scientists.

Heavy-duty vehicles contribute 23% of transportation emissions of greenhouse gases and account for almost one-quarter of the fuel consumed annually in the U.S. Credit: Chris Bair/Unsplash

Through a consortium of Department of Energy national laboratories, ORNL scientists are applying their expertise to provide solutions that enable the commercialization of emission-free hydrogen fuel cell technology for heavy-duty

Rich Giannone uses bioanalytical mass spectrometry to examine proteins, the primary driver in biological systems.

Rich Giannone uses bioanalytical mass spectrometry to examine proteins, the primary driver in biological systems.

ORNL researchers used electron beam powder bed fusion to produce refractory metal molybdenum, which remained crack free and dense, proving its viability for additive manufacturing applications. Credit: ORNL/U.S. Dept. of Energy

Oak Ridge National Laboratory scientists proved molybdenum titanium carbide, a refractory metal alloy that can withstand extreme temperature environments, can also be crack free and dense when produced with electron beam powder bed fusion. 

An ORNL-invented electrocatalyst made of custom-designed alloy nanoparticles embedded in carbon nanospikes was licensed by Prometheus Fuels and further developed to aid a process to convert solar and wind electricity into chemical energy for electrofuels. Credit: ORNL, U.S. Dept. of Energy

In a new twist to an existing award-winning ORNL technology, researchers have developed an electrocatalyst that enables water and carbon dioxide to be split and the atoms recombined to form higher weight hydrocarbons for gasoline, diesel and jet fuel.

ORNL researchers used fiber reinforcements made of steel, glass and carbon to develop a concrete mix that demonstrated high early strength within six hours of production, which is needed for the precast concrete industry. Credit: ORNL/U.S. Dept. of Energy

A team of researchers at Oak Ridge National Laboratory and the University of Tennessee have developed a concrete mix that demonstrated high early strength within six hours of mixing, potentially doubling the production capacity for the precast industry.

ATOM logo

The Accelerating Therapeutics for Opportunities in Medicine , or ATOM, consortium today announced the U.S. Department of Energy’s Oak Ridge, Argonne and Brookhaven national laboratories are joining the consortium to further develop ATOM’s artificial intelligence, or AI-driven, drug discovery platform.

Targeted alpha therapy can deliver radiation to specific cells, with minimal effect on surrounding, healthy cells. Credit: Michelle Lehman and Jaimee Janiga/ORNL, U.S. Dept. of Energy

A rare isotope in high demand for treating cancer is now more available to pharmaceutical companies developing and testing new drugs.

Neutron scattering experiments show electric charges, shown in red, blue and grey, in the SARS-CoV-2 main protease site where telaprevir binds to the structure. The experiments provide critical data for the design of small-molecule drugs to treat COVID-19. Credit: Jill Hemman and Michelle Lehman/ORNL, U.S. Dept. of Energy

Scientists have found new, unexpected behaviors when SARS-CoV-2 – the virus that causes COVID-19 – encounters drugs known as inhibitors, which bind to certain components of the virus and block its ability to reproduce.  

Researchers at ORNL and the University of Tennessee developed an automated workflow that combines chemical robotics and machine learning to speed the search for stable perovskites. Credit: Jaimee Janiga/ORNL, U.S. Dept of Energy

Researchers at the Department of Energy’s Oak Ridge National Laboratory and the University of Tennessee are automating the search for new materials to advance solar energy technologies.