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Alex Johs at ORNL's Spallation Neutron Source

Sometimes solutions to the biggest problems can be found in the smallest details. The work of biochemist Alex Johs at Oak Ridge National Laboratory bears this out, as he focuses on understanding protein structures and molecular interactions to resolve complex global problems like the spread of mercury pollution in waterways and the food supply.

Computing—Routing out the bugs

A study led by Oak Ridge National Laboratory explored the interface between the Department of Veterans Affairs’ healthcare data system and the data itself to detect the likelihood of errors and designed an auto-surveillance tool

Using artificial intelligence, Oak Ridge National Laboratory analyzed data from published medical studies to reveal the potential of direct and indirect impacts of bullying.

Oak Ridge National Laboratory is using artificial intelligence to analyze data from published medical studies associated with bullying to reveal the potential of broader impacts, such as mental illness or disease. 

Molecular dynamics simulations of the Fs-peptide revealed the presence of at least eight distinct intermediate stages during the process of protein folding. The image depicts a fully folded helix (1), various transitional forms (2–8), and one misfolded state (9). By studying these protein folding pathways, scientists hope to identify underlying factors that affect human health.

Using artificial neural networks designed to emulate the inner workings of the human brain, deep-learning algorithms deftly peruse and analyze large quantities of data. Applying this technique to science problems can help unearth historically elusive solutions.

(From left) ORNL Associate Laboratory Director for Computing and Computational Sciences Jeff Nichols; ORNL Health Data Sciences Institute Director Gina Tourassi; DOE Deputy Under Secretary for Science Thomas Cubbage; ORNL Task Lead for Biostatistics Blair Christian; and ORNL Research Scientist Ioana Danciu were invited to the White House to showcase an ORNL-developed digital tool aimed at better matching cancer patients with clinical trials.

OAK RIDGE, Tenn., March 4, 2019—A team of researchers from the Department of Energy’s Oak Ridge National Laboratory Health Data Sciences Institute have harnessed the power of artificial intelligence to better match cancer patients with clinical trials.

An ORNL-developed graphite foam, which could be used in plasma-facing components in fusion reactors, performed well during testing at the Wendlestein 7-X stellarator in Germany.

Scientists have tested a novel heat-shielding graphite foam, originally created at Oak Ridge National Laboratory, at Germany’s Wendelstein 7-X stellarator with promising results for use in plasma-facing components of fusion reactors.

ORNL scientists used commuting behavior data from East Tennessee to demonstrate how machine learning models can easily accept new data, quickly re-train themselves and update predictions about commuting patterns. Credit: April Morton/Oak Ridge National La

Oak Ridge National Laboratory geospatial scientists who study the movement of people are using advanced machine learning methods to better predict home-to-work commuting patterns.

Default image of ORNL entry sign

If you ask the staff and researchers at the Department of Energy’s Oak Ridge National Laboratory how they were first referred to the lab, you will get an extremely varied list of responses. Some may have come here as student interns, some grew up in the area and knew the lab by ...

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Biologists from Oak Ridge National Laboratory and the Smithsonian Environmental Research Center have confirmed that microorganisms called methanogens can transform mercury into the neurotoxin methylmercury with varying efficiency across species.

Lauren Garrison

The materials inside a fusion reactor must withstand one of the most extreme environments in science, with temperatures in the thousands of degrees Celsius and a constant bombardment of neutron radiation and deuterium and tritium, isotopes of hydrogen, from the volatile plasma at th...