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Shown here is the structure of the NEMO protein. A team from ORNL conducted extensive molecular dynamics work on Summit by using both quantum mechanics and machine-learning methods to look at the binding affinity of NEMO and 3CLpro in humans and other species and to consider the structural models derived from the sequences of other coronaviruses. Image courtesy Nature Communications, Dan Jacobson/ORNL.

A new paper published in Nature Communications adds further evidence to the bradykinin storm theory of COVID-19’s viral pathogenesis — a theory that was posited two years ago by a team of researchers at the Department of Energy’s Oak Ridge National Laboratory.

ORNL fusion technology scientist Tim Bigelow, right, stands near the control console in ORNL’s  fusion control room with Matt Houde of Quaise Energy. Their partnership aims to tackle technical challenges with the Millimeter Wave Drilling System that Quaise has developed. Credit: Carlos Jones/ORNL, U.S. Dept. of Energy.

Researchers in the geothermal energy industry are joining forces with fusion experts at ORNL to repurpose gyrotron technology, a tool used in fusion. Gyrotrons produce high-powered microwaves to heat up fusion plasmas.

A team of researchers used mathematics to predict which areas of the SARS-CoV-2 spike protein are most likely to mutate. Credit: Jill Hemman/ORNL, U.S. Dept. of Energy

Researchers from ORNL, the University of Tennessee at Chattanooga and Tuskegee University used mathematics to predict which areas of the SARS-CoV-2 spike protein are most likely to mutate.

ORNL’s Valentino Cooper will direct a new DOE Energy Frontier Research Center focused on polymer electrolytes for solid-state batteries. Credit: Carlos Jones/ORNL, U.S. Dept. of Energy

ORNL has been selected to lead an Energy Frontier Research Center, or EFRC, focused on polymer electrolytes for next-generation energy storage devices such as fuel cells and solid-state electric vehicle batteries.

Technology Innovation Program

Five technologies invented by scientists at the Department of Energy’s Oak Ridge National Laboratory have been selected for targeted investment through ORNL’s Technology Innovation Program.

Data from different sources are joined on platforms created by ORNL researchers to offer better information for decision makers. Credit: ORNL/Nathan Armistead

When the COVID-19 pandemic stunned the world in 2020, researchers at ORNL wondered how they could extend their support and help

Samarthya Bhagia examines a sample of a thermoplastic composite material additively manufactured using poplar wood and polylactic acid. Credit: Carlos Jones/ORNL, U.S. Dept. of Energy

Chemical and environmental engineer Samarthya Bhagia is focused on achieving carbon neutrality and a circular economy by designing new plant-based materials for a range of applications from energy storage devices and sensors to environmentally friendly bioplastics.

ORNL polymer scientists Tomonori Saito, left, and Sungjin Kim upcycled waste plastic to create a stronger, tougher, solvent-resistant material for new additive manufacturing applications. Credit: Genevieve Martin/ORNL, U.S. Dept. of Energy

ORNL researchers have developed an upcycling approach that adds value to discarded plastics for reuse in additive manufacturing, or 3D printing.

ORNL’s Bruce Pint, left, and Marie Romedenne review experiment results. Credit: ORNL, U.S. Dept. of Energy

Practical fusion energy is not just a dream at ORNL. Experts in fusion and material science are working together to develop solutions that will make a fusion pilot plant — and ultimately carbon-free, abundant fusion electricity — possible.

Frontier has arrived, and ORNL is preparing for science on Day One. Credit: Carlos Jones/ORNL, Dept. of Energy

The Frontier supercomputer at the Department of Energy’s Oak Ridge National Laboratory earned the top ranking today as the world’s fastest on the 59th TOP500 list, with 1.1 exaflops of performance. The system is the first to achieve an unprecedented level of computing performance known as exascale, a threshold of a quintillion calculations per second.