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ORNL scientists mutated amino acids in a receptor protein, shown in green, which diminished interaction with the SARS-CoV-2 virus spike protein, shown in red. Mutating the receptor protein hampered the virus’s ability to infect host cells. Credit: ORNL, U.S. Dept. of Energy

Oak Ridge National Laboratory scientists exploring bioenergy plant genetics have made a surprising discovery: a protein domain that could lead to new COVID-19 treatments.

Oak Ridge National Laboratory led a team of scientists to design a molecule that disrupts the infection mechanism of the SARS-CoV-2 coronavirus and could be used to develop new treatments for COVID-19 and future virus outbreaks. Credit: Michelle Lehman/ORNL, U.S. Dept. of Energy

A team of scientists led by the Department of Energy’s Oak Ridge National Laboratory designed a molecule that disrupts the infection mechanism of the SARS-CoV-2 coronavirus and could be used to develop new treatments for COVID-19 and other viral diseases.

A researcher works in a lab in the Radiochemical Engineering and Development Center, or REDC,  at ORNL’s main campus. The REDC provides world-class capabilities in isotope production, research and development, source fabrication, and the distribution of various unique isotopes. Here, experts handle some of the most exotic materials in the world. Credit: Carlos Jones, ORNL/U.S. Dept. of Energy

A series of new classes at Pellissippi State Community College will offer students a new career path — and a national laboratory a pipeline of workers who have the skills needed for its own rapidly growing programs.

Pm-147

With larger, purer shipments on a more frequent basis, Oak Ridge National Laboratory is moving closer to routine production of promethium-147. That’s thanks in part to the application of some specific research performed a decade ago for a completely different project.

Jason Gardner, Sandra Davern and Peter Thornton have been elected fellows of AAAS. Credit: Laddy Fields/ORNL, U.S. Dept. of Energy

Three scientists from the Department of Energy’s Oak Ridge National Laboratory have been elected fellows of the American Association for the Advancement of Science, or AAAS.

Nearly $500 million in Inflation Reduction Act funding will support several key science projects underway at ORNL. Credit: ORNL/U.S. Dept. of Energy

Several significant science and energy projects led by the ORNL will receive a total of $497 million in funding from the Inflation Reduction Act.

U.S. Secretary of Energy Jennifer Granholm visited Oak Ridge National Laboratory today to attend a groundbreaking ceremony for the U.S. Stable Isotope Research and Development Center. The facility is slated to receive $75 million in funding from the Inflation Reduction Act.

U.S. Secretary of Energy Jennifer Granholm visited Oak Ridge National Laboratory today to attend a groundbreaking ceremony for the U.S. Stable Isotope Production and Research Center. The facility is slated to receive $75 million in funding from the Inflation Reduction Act.

ORNL’s Adam Guss and colleagues used synthetic biology to develop a custom microbe capable of converting deconstructed mixed plastic waste into valuable new materials. Credit: Carlos Jones/ORNL, U.S. Dept. of Energy

Scientists working on a solution for plastic waste have developed a two-step chemical and biological process to break down and upcycle mixed plastics into valuable bioproducts.

Researchers at Oak Ridge National Laboratory probed the chemistry of radium to gain key insights on advancing cancer treatments using radiation therapy. Credit: Adam Malin/ORNL, U.S. Dept. of Energy

Researchers at ORNL explored radium’s chemistry to advance cancer treatments using ionizing radiation.

Oak Ridge National Laboratory’s Mitch Allmond works with the Facility for Rare Isotope Beams Decay Station initiator, which combined diverse detectors for FRIB’s first experiment. Credit: Robert Grzywacz/ORNL, U.S. Dept. of Energy

Two decades in the making, a new flagship facility for nuclear physics opened on May 2, and scientists from the Department of Energy’s Oak Ridge National Laboratory have a hand in 10 of its first 34 experiments.