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ORNL’s Josh Michener, a microbiologist and metabolic engineer, led the discovery of a useful new enzyme that breaks down stubborn bonds in lignin, a polymer found in plants that typically becomes waste during bioconversion. Credit: Carlos Jones/ORNL, U.S. Dept. of Energy

In a step toward increasing the cost-effectiveness of renewable biofuels and bioproducts, scientists at ORNL discovered a microbial enzyme that degrades tough-to-break bonds in lignin, a waste product of biorefineries.

Scientists genetically engineered bacteria for itaconic acid production, creating dynamic controls that separate microbial growth and production phases for increased efficiency and acid yield. Credit: NREL

A research team led by Oak Ridge National Laboratory bioengineered a microbe to efficiently turn waste into itaconic acid, an industrial chemical used in plastics and paints.

Associate Laboratory Director Kathy McCarthy heads the ORNL directorate that manages proto-MPEX, a linear plasma device that informs the development of the MPEX tool for study of fusion materials. Credit: Carlos Jones/ORNL, U.S. Dept. of Energy

From the helm of a one-of-a-kind organization that brings nuclear fusion and fission expertise together to pave the way to expanding carbon-free energy, Kathy McCarthy can trace the first step of her engineering career back to

Distinguished Inventors

Six scientists at the Department of Energy’s Oak Ridge National Laboratory were named Battelle Distinguished Inventors, in recognition of obtaining 14 or more patents during their careers at the lab.

Researchers Adam Guss and Melissa Tumen-Velasquez work with microbes to understand how the organisms consume plastics and break them into chemical components that can be used to make higher-value products.

From soda bottles to car bumpers to piping, electronics, and packaging, plastics have become a ubiquitous part of our lives. 

Water from local creeks now flows through these simulated streams in the Aquatic Ecology Laboratory, providing new opportunities to study mercury pollution and advance solutions. Credit: ORNL, U.S. Dept. of Energy

New capabilities and equipment recently installed at the Department of Energy’s Oak Ridge National Laboratory are bringing a creek right into the lab to advance understanding of mercury pollution and accelerate solutions.

ORNL scientists have optimized the Pseudomonas putida bacterium to digest five of the most abundant components of lignocellulosic biomass simultaneously, supporting a highly efficient conversion process to create renewable fuels and chemicals from plants. Credit: Alli Werner/NREL,U.S. Dept of Energy

ORNL scientists have modified a single microbe to simultaneously digest five of the most abundant components of lignocellulosic biomass, a big step forward in the development of a cost-effective biochemical conversion process to turn plants into 

Nuclear – Finally, a benchmark

In the 1960s, Oak Ridge National Laboratory's four-year Molten Salt Reactor Experiment tested the viability of liquid fuel reactors for commercial power generation. Results from that historic experiment recently became the basis for the first-ever molten salt reactor benchmark.

A new method uses E. coli to generate DNA with methylation patterns that target microbes recognize and accept as their own, facilitating customization of microbes for biofuels production.

Scientists at the US Department of Energy’s Oak Ridge National Laboratory have demonstrated a method to insert genes into a variety of microorganisms that previously would not accept foreign DNA, with the goal of creating custom microbes to break down plants for bioenergy.

Alex Johs at ORNL's Spallation Neutron Source

Sometimes solutions to the biggest problems can be found in the smallest details. The work of biochemist Alex Johs at Oak Ridge National Laboratory bears this out, as he focuses on understanding protein structures and molecular interactions to resolve complex global problems like the spread of mercury pollution in waterways and the food supply.