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Molecular dynamics simulations of the Fs-peptide revealed the presence of at least eight distinct intermediate stages during the process of protein folding. The image depicts a fully folded helix (1), various transitional forms (2–8), and one misfolded state (9). By studying these protein folding pathways, scientists hope to identify underlying factors that affect human health.

Using artificial neural networks designed to emulate the inner workings of the human brain, deep-learning algorithms deftly peruse and analyze large quantities of data. Applying this technique to science problems can help unearth historically elusive solutions.

(From left) ORNL Associate Laboratory Director for Computing and Computational Sciences Jeff Nichols; ORNL Health Data Sciences Institute Director Gina Tourassi; DOE Deputy Under Secretary for Science Thomas Cubbage; ORNL Task Lead for Biostatistics Blair Christian; and ORNL Research Scientist Ioana Danciu were invited to the White House to showcase an ORNL-developed digital tool aimed at better matching cancer patients with clinical trials.

OAK RIDGE, Tenn., March 4, 2019—A team of researchers from the Department of Energy’s Oak Ridge National Laboratory Health Data Sciences Institute have harnessed the power of artificial intelligence to better match cancer patients with clinical trials.

ORNL scientists used commuting behavior data from East Tennessee to demonstrate how machine learning models can easily accept new data, quickly re-train themselves and update predictions about commuting patterns. Credit: April Morton/Oak Ridge National La

Oak Ridge National Laboratory geospatial scientists who study the movement of people are using advanced machine learning methods to better predict home-to-work commuting patterns.

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Biologists from Oak Ridge National Laboratory and the Smithsonian Environmental Research Center have confirmed that microorganisms called methanogens can transform mercury into the neurotoxin methylmercury with varying efficiency across species.

ORNL’s Steven Young (left) and Travis Johnston used Titan to prove the design and training of deep learning networks could be greatly accelerated with a capable computing system.

A team of researchers from the Department of Energy’s Oak Ridge National Laboratory has married artificial intelligence and high-performance computing to achieve a peak speed of 20 petaflops in the generation and training of deep learning networks on the

As hurricanes formed in the Gulf Coast, ORNL activated a computing technique to quickly gather building structure data from Texas’ coastal counties. Credit: Mark Tuttle/Oak Ridge National Laboratory, U.S. Dept. of Energy

Geospatial scientists at Oak Ridge National Laboratory have developed a novel method to quickly gather building structure datasets that support emergency response teams assessing properties damaged by Hurricanes Harvey and Irma. By coupling deep learning with high-performance comp...

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A team led by the Department of Energy’s Oak Ridge National Laboratory has identified a novel microbial process that can break down toxic methylmercury in the environment, a fundamental scientific discovery that could potentially reduce mercury toxicity levels and sup...

By wet-sieving stream sediment, (from left) Oak Ridge National Laboratory’s Kenneth Lowe, Melanie Mayes and John Dickson sort sediment into different particle size in this stream near Rocky Top.

An Oak Ridge National Laboratory study is providing an unprecedented watershed-scale understanding of mercury in soils and sediments. Researchers focused on evaluating mercury and soil properties along the banks of a mercury-contaminated stream in Oak Ridge, Tenn., sampling 145 loca...

Andrew King loads a gel with amplified gene fragments to detect the presence of mercury methylation genes in samples from East Fork Poplar Creek in Oak Ridge.

Environmental scientists can more efficiently detect genes required to convert mercury in the environment into more toxic methylmercury with molecular probes developed by researchers at the Department of Energy’s Oak Ridge National Laboratory. “We now have a quic...