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When exposed to radiation, electrons produced within molten zinc chloride, or ZnCl2, can be observed in three distinct singly occupied molecular orbital states, plus a more diffuse, delocalized state. Credit: Hung H. Nguyen/University of Iowa

In a finding that helps elucidate how molten salts in advanced nuclear reactors might behave, scientists have shown how electrons interacting with the ions of the molten salt can form three states with different properties. Understanding these states can help predict the impact of radiation on the performance of salt-fueled reactors.

Susan Hubbard, ORNL’s deputy for science and technology and Quincy Quick, TSU’s associate vice president for Research and Sponsored Programs, sign a memorandum of understanding to strengthen research cooperation and provide diverse undergraduate students enriching educational research opportunities at the lab. Credit: Carlos Jones/ORNL, U.S. Dept. of Energy

The Department of Energy’s Oak Ridge National Laboratory and Tennessee State University have signed a memorandum of understanding to strengthen research cooperation and provide diverse undergraduate students enriching educational research opportunities at the lab.

Susan Hubbard, ORNL’s deputy for science and technology and Can (John) Saygin, senior vice president for research and dean of the graduate college at UTRGV, sign a memorandum of understanding to strengthen research cooperation and establish a collaborative program for undergraduate research and education. Credit: Carlos Jones/ORNL, U.S. Dept. of Energy

ORNL and the University of Texas Rio Grande Valley, known as UTRGV, have signed a memorandum of understanding to strengthen research cooperation and establish a collaborative program for undergraduate research and education, further cementing hi

Susan Hubbard, diputada de Ciencia y Tecnología en ORNL, Can (John) Saygin, vicepresidente mayor de investigación y decano del Colegio de la Escuela de Postgrados en UTGRV, firman un Memorándum de Entendimiento comprometiéndose a fortalecer la cooperación en la investigación científica y establecer un programa colaborativo para estudiantes de pregrado. Crédito de la fotografía: Carlos Jones/ORNL, U.S. Dept. of Energy

Susan Hubbard, diputada de Ciencia y Tecnología en ORNL, Can (John) Saygin, vicepresidente mayor de investigación y decano del Colegio de la Escuela de Postgrados en UTGRV, firman un Memorándum de Entendimiento comprometiéndose a fortalecer

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Scientist-inventors from ORNL will present seven new technologies during the Technology Innovation Showcase on Friday, July 14, from 8 a.m.–4 p.m. at the Joint Institute for Computational Sciences on ORNL’s campus.

Jerry Parks leads the Molecular Biophysics group at ORNL, leveraging his expertise in computational chemistry and bioinformatics to unlock the inner workings of proteins—molecules that govern cellular structure and function and are essential to life. Credit: Genevieve Martin, ORNL/U.S. Dept. of Energy

When reading the novel Jurassic Park as a teenager, Jerry Parks found the passages about gene sequencing and supercomputers fascinating, but never imagined he might someday pursue such futuristic-sounding science.

ORNL scientists mutated amino acids in a receptor protein, shown in green, which diminished interaction with the SARS-CoV-2 virus spike protein, shown in red. Mutating the receptor protein hampered the virus’s ability to infect host cells. Credit: ORNL, U.S. Dept. of Energy

Oak Ridge National Laboratory scientists exploring bioenergy plant genetics have made a surprising discovery: a protein domain that could lead to new COVID-19 treatments.

Oak Ridge National Laboratory led a team of scientists to design a molecule that disrupts the infection mechanism of the SARS-CoV-2 coronavirus and could be used to develop new treatments for COVID-19 and future virus outbreaks. Credit: Michelle Lehman/ORNL, U.S. Dept. of Energy

A team of scientists led by the Department of Energy’s Oak Ridge National Laboratory designed a molecule that disrupts the infection mechanism of the SARS-CoV-2 coronavirus and could be used to develop new treatments for COVID-19 and other viral diseases.

Shown here is the structure of the NEMO protein. A team from ORNL conducted extensive molecular dynamics work on Summit by using both quantum mechanics and machine-learning methods to look at the binding affinity of NEMO and 3CLpro in humans and other species and to consider the structural models derived from the sequences of other coronaviruses. Image courtesy Nature Communications, Dan Jacobson/ORNL.

A new paper published in Nature Communications adds further evidence to the bradykinin storm theory of COVID-19’s viral pathogenesis — a theory that was posited two years ago by a team of researchers at the Department of Energy’s Oak Ridge National Laboratory.

A team of researchers used mathematics to predict which areas of the SARS-CoV-2 spike protein are most likely to mutate. Credit: Jill Hemman/ORNL, U.S. Dept. of Energy

Researchers from ORNL, the University of Tennessee at Chattanooga and Tuskegee University used mathematics to predict which areas of the SARS-CoV-2 spike protein are most likely to mutate.