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Different groups of proteins shown in different colors combine and attach to a broken strand of DNA.

Researchers at Georgia State University used the Summit supercomputer to study an elaborate molecular pathway called nucleotide excision repair. Decoding NER’s sophisticated sequence of events and the role of PInC in the pathway could provide key insights into developing novel treatments and preventing conditions that lead to premature aging and certain types of cancer.

Procter & Gamble scientists used ORNL’s Summit supercomputer to create a digital model of the corneal epithelium, the primary outer layer of cells covering the human eye, and test that model against a series of cleaning compounds in search of a gentler, more environmentally sustainable formula.

P&G is using simulations on the ORNL Summit supercomputer to study how surfactants in cleaners cause eye irritation. By modeling the corneal epithelium, P&G aims to develop safer, concentrated cleaning products that meet performance and safety standards while supporting sustainability goals.

Two pictures of a rounded triangle shape are shown in mirror image. The left is white with red and purple spots in the middle while the one on the right is purple with a yellow and blue ring in the middle

Scientists designing the world’s first controlled nuclear fusion power plant, ITER, needed to solve the problem of runaway electrons, negatively charged particles in the soup of matter in the plasma within the tokamak, the magnetic bottle intended to contain the massive energy produced. Simulations performed on Summit, the 200-petaflop supercomputer at ORNL, could offer the first step toward a solution.

Photo is a high aerial view of lake superior through the clouds

Researchers at Stanford University, the European Center for Medium-Range Weather Forecasts, or ECMWF, and ORNL used the lab’s Summit supercomputer to better understand atmospheric gravity waves, which influence significant weather patterns that are difficult to forecast. 

Summit Supercomputer

Scientists conducted a groundbreaking study on the genetic data of over half a million U.S. veterans, using tools from the Oak Ridge National Laboratory to analyze 2,068 traits from the Million Veteran Program.

The summit supercomputer logo on a computer cabinet off center going to the left. There are 7 cabinets going off to the left.

The Summit supercomputer did not have its many plugs pulled as planned after its five years of service. Instead, a new DOE Office of Science-backed allocation program called SummitPLUS was launched, extending Summit's production for another year. What did we learn during Summit’s bonus year of scientific discovery? Here are five projects with important results.

Black computing cabinets in a row on a white floor in the data center that houses the Frontier supercomputer at Oak Ridge National Laboratory

Two-and-a-half years after breaking the exascale barrier, the Frontier supercomputer at the Department of Energy’s Oak Ridge National Laboratory continues to set new standards for its computing speed and performance.

Frontier supercomputer is pictured here with the logo on the cabinets

A multi-institutional team of researchers led by the King Abdullah University of Science and Technology, or KAUST, Saudi Arabia, has been nominated for the Association for Computing Machinery’s 2024 Gordon Bell Prize for Climate Modelling. 

Supriya Chinthavali is standing with the Summit supercomputer at ORNL

The Department of Energy’s Office of Electricity, in partnership with ORNL, has launched an experimental platform for energy sector-related data with enhanced emphasis on governance and usability. 

Larry York is sitting in front of a computer screen showing an image of plant phenotyping

The Advanced Plant Phenotyping Laboratory at ORNL utilizes robotics, multi-modal imaging, and AI to enhance understanding of plant genetics and interactions with microbes. It aims to connect genes to traits for advancements in bioenergy, agriculture, and climate resilience. Senior scientist Larry York highlights the lab's capabilities and the insights from a new digital underground imaging system to improve biomass feedstocks for bioenergy and carbon storage.