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Media Contacts
![An ORNL-led team studied the SARS-CoV-2 spike protein in the trimer state, shown here, to pinpoint structural transitions that could be disrupted to destabilize the protein and negate its harmful effects. Credit: Debsindhu Bhowmik/ORNL, U.S. Dept. of Energy](/sites/default/files/styles/list_page_thumbnail/public/2022-01/sars_cov_2_bk.png?h=05c2797f&itok=jQ2D9aTr)
To explore the inner workings of severe acute respiratory syndrome coronavirus 2, or SARS-CoV-2, researchers from ORNL developed a novel technique.
![ORNL researchers proved that COVID-19 vaccines can be kept ultra-cool for an extended period in a retrofitted commercial storage container, providing a resource for safe delivery to remote locations. Credit: ORNL, U.S. Dept. of Energy](/sites/default/files/styles/list_page_thumbnail/public/2022-01/UnitOnTestSite_0.jpg?h=71976bb4&itok=HEVKqbrK)
Oak Ridge National Laboratory researchers have retrofitted a commercial refrigeration container designed to ensure COVID-19 vaccines remain at ultra-low temperatures during long transport and while locally stored.
![Researchers used an atomic force microscope to test how easily particles of the novel coronavirus cling to certain surfaces, a property known as adhesion energy. Credit: Ali Passian/ORNL, U.S. Dept. of Energy](/sites/default/files/styles/list_page_thumbnail/public/2021-11/AFM-COVID%20story%20tip_0.png?h=2e111cc1&itok=GP6NSVOx)
A study by Department of Energy researchers detailed a potential method to detect the novel coronavirus
![ORNL researchers produced self-healable and highly adhesive elastomers, proving they self-repair in ambient conditions and underwater. This project garnered a 2021 R&D 100 Award. Credit: ORNL, U.S. Dept. of Energy](/sites/default/files/styles/list_page_thumbnail/public/2021-10/Unbreakable-bond-copy.jpg?h=cd715a88&itok=cQeEYNZn)
Research teams from the Department of Energy’s Oak Ridge National Laboratory and their technologies have received seven 2021 R&D 100 Awards, plus special recognition for a COVID-19-related project.
![An ORNL-led team comprising researchers from multiple DOE national laboratories is using artificial intelligence and computational screening techniques – in combination with experimental validation – to identify and design five promising drug therapy approaches to target the SARS-CoV-2 virus. Credit: Michelle Lehman/ORNL, U.S. Dept. of Energy](/sites/default/files/styles/list_page_thumbnail/public/2021-06/frame1.png?h=d1cb525d&itok=51pwBWyP)
An ORNL-led team comprising researchers from multiple DOE national laboratories is using artificial intelligence and computational screening techniques – in combination with experimental validation – to identify and design five promising drug therapy approaches to target the SARS-CoV-2 virus.
![Parans Paranthaman, a researcher in the Chemical Sciences Division at ORNL, coordinated research efforts to study the filter efficiency of the N95 material. His published results represent one of the first studies on polypropylene as it relates to COVID-19. Credit: ORNL/U.S. Dept. of Energy](/sites/default/files/styles/list_page_thumbnail/public/2021-04/2021-P01675.jpg?h=18f5407d&itok=B3UCcJxT)
When COVID-19 was declared a pandemic in March 2020, Oak Ridge National Laboratory’s Parans Paranthaman suddenly found himself working from home like millions of others.
![Kashif Nawaz, researcher and group leader for multifunctional equipment integration in buildings technologies, is developing a platform for the direct air capture of carbon dioxide that can be retrofitted to existing rooftop heating, ventilation and air conditioning units. Credit: ORNL/U.S. Dept. of Energy](/sites/default/files/styles/list_page_thumbnail/public/2021-03/2021-P01088_small.jpg?h=036a71b7&itok=iOYUTtfS)
When Kashif Nawaz looks at a satellite map of the U.S., he sees millions of buildings that could hold a potential solution for the capture of carbon dioxide, a plentiful gas that can be harmful when excessive amounts are released into the atmosphere, raising the Earth’s temperature.
![Neutron scattering experiments show electric charges, shown in red, blue and grey, in the SARS-CoV-2 main protease site where telaprevir binds to the structure. The experiments provide critical data for the design of small-molecule drugs to treat COVID-19. Credit: Jill Hemman and Michelle Lehman/ORNL, U.S. Dept. of Energy](/sites/default/files/styles/list_page_thumbnail/public/2021-03/after_transprent_background-wFill.png?h=c71d0c67&itok=jGFt_Ggj)
Scientists have found new, unexpected behaviors when SARS-CoV-2 – the virus that causes COVID-19 – encounters drugs known as inhibitors, which bind to certain components of the virus and block its ability to reproduce.
![ORNL has modeled the spike protein that binds the novel coronavirus to a human cell for better understanding of the dynamics of COVID-19. Credit: Stephan Irle/ORNL, U.S. Dept. of Energy](/sites/default/files/styles/list_page_thumbnail/public/2021-02/toc_notext_0.png?h=3474dc74&itok=zSrqLz3F)
To better understand the spread of SARS-CoV-2, the virus that causes COVID-19, Oak Ridge National Laboratory researchers have harnessed the power of supercomputers to accurately model the spike protein that binds the novel coronavirus to a human cell receptor.
![ORNL recognized the small businesses that have made a positive impact on ORNL’s operations at the virtual 2020 Small Business Awards. Credit: ORNL, U.S. Dept. of Energy](/sites/default/files/styles/list_page_thumbnail/public/2020-11/2013-P05160-cropped_0.jpg?h=8f74817f&itok=VU4aJf_i)
Thirty-two Oak Ridge National Laboratory employees were named among teams recognized by former DOE Secretary Dan Brouillette with Secretary’s Honor Awards as he completed his term. Four teams received new awards that reflect DOE responses to the coronavirus pandemic.