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Genetic analysis revealed connections between inflammatory activity and development of atomic dermatitis, according to researchers from the UPenn School of Medicine, the Perelman School of Medicine, and Oak Ridge National Laboratory. Credit: Kang Ko/UPenn

University of Pennsylvania researchers called on computational systems biology expertise at Oak Ridge National Laboratory to analyze large datasets of single-cell RNA sequencing from skin samples afflicted with atopic dermatitis.

Scientists from LanzaTech, Northwestern University and Oak Ridge National Laboratory engineered a microbe, shown in light blue, to convert molecules of industrial waste gases, such as carbon dioxide and carbon monoxide, into acetone. The same microbe can also make isopropanol. Credit: Andy Sproles/ORNL, U.S. Dept. of Energy

A team of scientists from LanzaTech, Northwestern University and ORNL have developed carbon capture technology that harnesses emissions from industrial processes to produce acetone and isopropanol

A new process developed by Oak Ridge National Laboratory leverages deep learning techniques to study cell movements in a simulated environment, guided by simple physics rules similar to video-game play. Credit: MSKCC and UTK

Scientists have developed a novel approach to computationally infer previously undetected behaviors within complex biological environments by analyzing live, time-lapsed images that show the positioning of embryonic cells in C. elegans, or roundworms. Their published methods could be used to reveal hidden biological activity. 

Three ORNL scientists have been elected fellows of the American Association for the Advancement of Science, or AAAS, the world’s largest general scientific society and publisher of the Science family of journals. Credit: ORNL, U.S. Dept. of Energy

Three ORNL scientists have been elected fellows of the American Association for the Advancement of Science, or AAAS, the world’s largest general scientific society and publisher of the Science family of journals.

ORNL Corporate Research Fellow and Geospatial Science and Human Security Division Director Budhu Bhaduri has been elected as a fellow of the American Association of Geographers. The honor recognizes Bhaduri for his “innovation, mentorship and wide-ranging leadership” in geographic sciences. Credit: ORNL, U.S. Dept. of Energy

ORNL’s Budhendra “Budhu” Bhaduri has been elected a fellow of the American Association of Geographers. The honor recognizes Bhaduri as “a world leader in innovation, development and application of research in human dynamics, geographic data science, remote sensing and scalable geocomputation.”

This protein drives key processes for sulfide use in many microorganisms that produce methane, including Thermosipho melanesiensis. Researchers used supercomputing and deep learning tools to predict its structure, which has eluded experimental methods such as crystallography.  Credit: Ada Sedova/ORNL, U.S. Dept. of Energy

A team of scientists led by the Department of Energy’s Oak Ridge National Laboratory and the Georgia Institute of Technology is using supercomputing and revolutionary deep learning tools to predict the structures and roles of thousands of proteins with unknown functions.

ORNL’s biosensor system reveals CRISPR activity in poplar plants, which glow bright green under ultraviolet light, compared to normal plants, which appear red. Credit: Guoliang Yuan/ORNL, U.S. Dept. of Energy

Detecting the activity of CRISPR gene editing tools in organisms with the naked eye and an ultraviolet flashlight is now possible using technology developed at ORNL. 

ORNL’s Larry York studies how plant root traits contribute to crop productivity. Credit: Carlos Jones/ORNL, U.S. Dept. of Energy

Biologist Larry York’s fascination with plant roots has spurred his research across four continents and inspired him to create accessible tools that enable others to explore the underground world.

Merlin Theodore, advanced fibers manufacturing group leader and Tuskegee University alumna, will guide Oak Ridge National Laboratory’s collaboration with the university, through which students and researchers work together to advance the development of bioderived materials. Credit: ORNL, U.S. Dept. of Energy

ORNL and Tuskegee University have formed a partnership to develop new biodegradable materials for use in buildings, transportation and biomedical applications.

By studying the activity patterns of populations around the world, scientists at ORNL are identifying the communities that are most likely to face extreme climate events and associated national security challenges. Credit: Erik Schmidt/ORNL, U.S. Dept. of Energy

Using novel data sets and computing systems, researchers at ORNL are simulating how climate change affects the safety and security of the country.