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Improvements in Level Set Segmentation of 3D Small Animal Imagery...

by Jeffery R Price, Deniz Aykac, Jonathan S Wall
Publication Type
Conference Paper
Publication Date
Page Number
651233
Volume
6512
Conference Name
SPIE Medical Imaging Symposium, Image Processing Conference
Conference Location
San Diego, California, United States of America
Conference Sponsor
SPIE
Conference Date
-

In this paper, we investigate several improvements to region-based level set algorithms in the context of seg- menting x-ray CT data from pre-clinical imaging of small animal models. We incorporate a recently introduced signed distance preserving term into a region-based level set model and provide formulas for a semi-implicit finite difference implementation. We illustrate some pitfalls of topology preserving level sets and introduce the concept of connectivity preservation as a potential alternative. We illustrate the benefits of these improvements on phantom and real data.