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The Accelerating Therapeutics for Opportunities in Medicine , or ATOM, consortium today announced the U.S. Department of Energy’s Oak Ridge, Argonne and Brookhaven national laboratories are joining the consortium to further develop ATOM’s artificial intelligence, or AI-driven, drug discovery platform.

Targeted alpha therapy can deliver radiation to specific cells, with minimal effect on surrounding, healthy cells. Credit: Michelle Lehman and Jaimee Janiga/ORNL, U.S. Dept. of Energy

A rare isotope in high demand for treating cancer is now more available to pharmaceutical companies developing and testing new drugs.

Data from the ORNL Free Air CO2 Enrichment experiment were combined with observations from more than 100 other FACE sites for this analysis, which revealed new insights about the relationship between plant biomass growth and soil carbon storage. Credit: Jeff Warren/ORNL, U.S. Dept. of Energy

Oak Ridge National Laboratory was among an international team, led by Lawrence Livermore National Laboratory, who synthesized 108 elevated carbon dioxide, or CO2, experiments performed in various ecosystems to find out how much carbon is

Kashif Nawaz, researcher and group leader for multifunctional equipment integration in buildings technologies, is developing a platform for the direct air capture of carbon dioxide that can be retrofitted to existing rooftop heating, ventilation and air conditioning units.  Credit: ORNL/U.S. Dept. of Energy

When Kashif Nawaz looks at a satellite map of the U.S., he sees millions of buildings that could hold a potential solution for the capture of carbon dioxide, a plentiful gas that can be harmful when excessive amounts are released into the atmosphere, raising the Earth’s temperature.

Neutron scattering experiments show electric charges, shown in red, blue and grey, in the SARS-CoV-2 main protease site where telaprevir binds to the structure. The experiments provide critical data for the design of small-molecule drugs to treat COVID-19. Credit: Jill Hemman and Michelle Lehman/ORNL, U.S. Dept. of Energy

Scientists have found new, unexpected behaviors when SARS-CoV-2 – the virus that causes COVID-19 – encounters drugs known as inhibitors, which bind to certain components of the virus and block its ability to reproduce.  

Data from the GEDI instrument on the International Space Station can help answer questions about Earth’s biomes and ecosystem impacts on the carbon cycle and climate. Credit: NASA

New data distributed through NASA’s Oak Ridge National Laboratory Distributed Active Archive Center, or ORNL DAAC, provide an unprecedented picture of plants’ carbon storage capacity around the globe.

Nesaraja split her effort between nuclear data evaluation and experimentation at ORNL’s now-closed Holifield Radioactive Ion Beam Facility. Credit: Carlos Jones/ORNL, U.S. Dept. of Energy

Nuclear physicist Caroline Nesaraja of the Department of Energy’s Oak Ridge National Laboratory evaluates nuclear data vital to applied and basic sciences. 

Urban climate modeling

Researchers at Oak Ridge National Laboratory have identified a statistical relationship between the growth of cities and the spread of paved surfaces like roads and sidewalks. These impervious surfaces impede the flow of water into the ground, affecting the water cycle and, by extension, the climate.

ORNL researchers combined additive manufacturing with conventional compression molding to produce high-performance thermoplastic composites, demonstrating the potential for the use of large-scale multimaterial preforms to create molded composites. Credit: ORNL/U.S. Dept. of Energy

Oak Ridge National Laboratory researchers combined additive manufacturing with conventional compression molding to produce high-performance thermoplastic composites reinforced with short carbon fibers.

Technicians John Dyer and T. Dyer use a manipulator arm in a shielded cave in ORNL’s Radiochemical Engineering Development Center to separate concentrated Pm-147 from byproducts generated through the production of Pu-238.

A new method developed at Oak Ridge National Laboratory proves one effort’s trash is another’s valuable isotope. One of the byproducts of the lab’s national plutonium-238 production program is promethium-147, a rare isotope used in nuclear batteries and to measure the thickness of materials.