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Neutron scattering experiments show electric charges, shown in red, blue and grey, in the SARS-CoV-2 main protease site where telaprevir binds to the structure. The experiments provide critical data for the design of small-molecule drugs to treat COVID-19. Credit: Jill Hemman and Michelle Lehman/ORNL, U.S. Dept. of Energy

Scientists have found new, unexpected behaviors when SARS-CoV-2 – the virus that causes COVID-19 – encounters drugs known as inhibitors, which bind to certain components of the virus and block its ability to reproduce.  

ORNL researchers combined additive manufacturing with conventional compression molding to produce high-performance thermoplastic composites, demonstrating the potential for the use of large-scale multimaterial preforms to create molded composites. Credit: ORNL/U.S. Dept. of Energy

Oak Ridge National Laboratory researchers combined additive manufacturing with conventional compression molding to produce high-performance thermoplastic composites reinforced with short carbon fibers.

Ken Andersen

Ken Andersen has been named associate laboratory director for the Neutron Sciences Directorate, or NScD, at the Department of Energy’s Oak Ridge National Laboratory.

The pressure cell uses two gem-quality synthetic opposing diamonds to exert extreme pressures on materials, providing fundamental insights into materials that only neutrons can reveal. Credit: Genevieve Martin/ORNL, U.S. Dept. of Energy

Researchers at Oak Ridge National Laboratory’s Spallation Neutron Source have developed a diamond anvil pressure cell that will enable high-pressure science currently not possible at any other neutron source in the world.

ORNL researchers used gas metal arc welding additive technology to print the die for a B-pillar or vertical roof support structure for a sport utility vehicle, demonstrating a 20% improvement in the cooling rate. Credit: ORNL/U.S. Dept. of Energy

A team of Oak Ridge National Laboratory researchers demonstrated that an additively manufactured hot stamping die – a tool used to create car body components – cooled faster than those produced by conventional manufacturing methods.

A 3D printed turbine blade demonstrates the use of the new class of nickel-based superalloys that can withstand extreme heat environments without cracking or losing strength. Credit: ORNL/U.S. Dept. of Energy

Oak Ridge National Laboratory researchers have demonstrated that a new class of superalloys made of cobalt and nickel remains crack-free and defect-resistant in extreme heat, making them conducive for use in metal-based 3D printing applications.

SCGSR Awardee Jacob Zettlemoyer, Indiana University Bloomington, led data analysis and worked with ORNL’s Mike Febbraro on coatings, shown under blue light, to shift argon light to visible wavelengths to boost detection. Credit: Rex Tayloe/Indiana University

The COHERENT particle physics experiment at the Department of Energy’s Oak Ridge National Laboratory has firmly established the existence of a new kind of neutrino interaction.

ORNL is designing a neutronic research engine to evaluate new materials and designs for advanced vehicles using the facilities at the Spallation Neutron Source at ORNL. Credit: Jill Hemman/ORNL, U.S. Dept of Energy, and  Southwest Research Institute.

In the quest for advanced vehicles with higher energy efficiency and ultra-low emissions, ORNL researchers are accelerating a research engine that gives scientists and engineers an unprecedented view inside the atomic-level workings of combustion engines in real time.

Six ORNL scientists have been elected as fellows to the American Association for the Advancement of Science, or AAAS. Credit: ORNL, U.S. Dept. of Energy

Six ORNL scientists have been elected as fellows to the American Association for the Advancement of Science, or AAAS.

An organic solvent and water separate and form nanoclusters on the hydrophobic and hydrophilic sections of plant material, driving the efficient deconstruction of biomass. Credit: Michelle Lehman/ORNL, U.S. Dept. of Energy

Experiments led by researchers at ORNL have determined that several hepatitis C drugs can inhibit the SARS-CoV-2 main protease, a crucial protein enzyme that enables the novel coronavirus to reproduce.