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Two hybrid poplar plants, middle and right, engineered with the PtrXB38 hub gene exhibited a drastic increase in root and callus formation compared with a wild-type control plant, left. Credit: Tao Yao/ORNL, U.S. Dept. of Energy

Oak Ridge National Laboratory scientists identified a gene “hotspot” in the poplar tree that triggers dramatically increased root growth. The discovery supports development of better bioenergy crops and other plants that can thrive in difficult conditions while storing more carbon belowground.

ORNL’s Jack Cahill, Eugene Dumitrescu, Dan Lu, Takaaki Koyanagi and Matthew Brahlek have been selected to receive Department of Energy Early Career Research awards. Credit: Carlos Jones/ORNL, U.S. Dept. of Energy.

Since its inception in 2010, the program bolsters national scientific discovery by supporting early career researchers in fields pertaining to the Office of Science.

Biopsy from the tubular esophagus showing incomplete intestinal metaplasia, goblet cells with interposed cells having gastric foveolar-type mucin consistent with Barrett esophagus. Negative for dysplasia. H&E stain. Credit: Creative Commons

A team including researchers from the Department of Energy’s Oak Ridge National Laboratory has developed a digital tool to better monitor a condition known as Barrett’s esophagus, which affects more than 3 million people in the United States.

Urban climate modeling

Researchers at Oak Ridge National Laboratory have identified a statistical relationship between the growth of cities and the spread of paved surfaces like roads and sidewalks. These impervious surfaces impede the flow of water into the ground, affecting the water cycle and, by extension, the climate.

Computing—Routing out the bugs

A study led by Oak Ridge National Laboratory explored the interface between the Department of Veterans Affairs’ healthcare data system and the data itself to detect the likelihood of errors and designed an auto-surveillance tool

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While studying the genes in poplar trees that control callus formation, scientists at Oak Ridge National Laboratory have uncovered genetic networks at the root of tumor formation in several human cancers.

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For decades, biologists have believed a key enzyme in plants had one function—produce amino acids, which are vital to plant survival and also essential to human diets. But for Wellington Muchero, Meng Xie and their colleagues, this enzyme does more than advertised. They had run a series of experiments on poplar plants that consistently revealed mutations in a structure of the life-sustaining enzyme that was not previously known to exist.

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A new process to identify certain microbes in women could be used to diagnose endometriosis without invasive surgery, even before symptoms start. A collaborative research team including Oak Ridge National Laboratory analyzed bacteria from a small sample of premenopausal women undergoing laparoscopic surgery for suspected endometriosis.
Brian Davison

Brian Davison, a researcher at the Department of Energy's Oak Ridge National Laboratory, has been awarded a 2017 fellowship by the Society for Industrial Microbiology and Biotechnology (SIMB).

GWAS SNP Populus trees under study

Researchers at the Department of Energy’s Oak Ridge National Laboratory (ORNL) have released the largest-ever single nucleotide polymorphism (SNP) dataset of genetic variations in poplar trees, information useful to plant scientists