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ORNL scientists developed a method that improves the accuracy of the CRISPR Cas9 gene editing tool used to modify microbes for renewable fuels and chemicals production. This research draws on the lab’s expertise in quantum biology, artificial intelligence and synthetic biology. Credit: Philip Gray/ORNL, U.S. Dept. of Energy

Scientists at ORNL used their expertise in quantum biology, artificial intelligence and bioengineering to improve how CRISPR Cas9 genome editing tools work on organisms like microbes that can be modified to produce renewable fuels and chemicals.

Connecting  wires to the interface of the topological insulator and superconductor enables probing of novel electronic properties. Researchers aim for qubits based on theorized Majorana particles. Credit: Carlos Jones/ORNL, U.S. Dept. of Energy

Quantum computers process information using quantum bits, or qubits, based on fragile, short-lived quantum mechanical states. To make qubits robust and tailor them for applications, researchers from the Department of Energy’s Oak Ridge National Laboratory sought to create a new material system.

Chlorella Vulgaris

In the search for ways to fight methylmercury in global waterways, scientists at Oak Ridge National Laboratory discovered that some forms of phytoplankton are good at degrading the potent neurotoxin.

Clouds of gray smoke in the lower left are funneled northward from wildfires in Western Canada, reaching the edge of the sea ice covering the Arctic Ocean. A second path of thick smoke is visible at the top center of the image, emanating from wildfires in the boreal areas of Russia’s Far East, in this image captured on July 13, 2023. Credit: NASA MODIS

Wildfires have shaped the environment for millennia, but they are increasing in frequency, range and intensity in response to a hotter climate. The phenomenon is being incorporated into high-resolution simulations of the Earth’s climate by scientists at the Department of Energy’s Oak Ridge National Laboratory, with a mission to better understand and predict environmental change.

Jerry Parks leads the Molecular Biophysics group at ORNL, leveraging his expertise in computational chemistry and bioinformatics to unlock the inner workings of proteins—molecules that govern cellular structure and function and are essential to life. Credit: Genevieve Martin, ORNL/U.S. Dept. of Energy

When reading the novel Jurassic Park as a teenager, Jerry Parks found the passages about gene sequencing and supercomputers fascinating, but never imagined he might someday pursue such futuristic-sounding science.

Researchers Melissa Cregger, left, and Xiaohan Yang examine plants in an ORNL greenhouse where biosensors are installed to accelerate plant transformations. Credit: Genevieve Martin/ORNL, U.S. Dept. of Energy.

Nature-based solutions are an effective tool to combat climate change triggered by rising carbon emissions, whether it’s by clearing the skies with bio-based aviation fuels or boosting natural carbon sinks.

When an electron beam drills holes in heated graphene, single-atom vacancies, shown in purple, diffuse until they join with other vacancies to form stationary structures and chains, shown in blue. Credit: Ondrej Dyck/ORNL, U.S. Dept. of Energy

Oak Ridge National Laboratory researchers serendipitously discovered when they automated the beam of an electron microscope to precisely drill holes in the atomically thin lattice of graphene, the drilled holes closed up.

A pure lipid membrane formed using lipid-coated water droplets exhibits long-term potentiation, or LTP, associated with learning and memory, emulating hippocampal LTP observed in the brains of mammals and birds. Credit: Jill Hemman/ORNL, U.S. Dept. of Energy

While studying how bio-inspired materials might inform the design of next-generation computers, scientists at ORNL achieved a first-of-its-kind result that could have big implications for both edge computing and human health.

ORNL researchers led by Michael Garvin, left, and David Kainer discovered genetic mutations called structural variants and linked them to autism spectrum disorders, demonstrating an approach that could be used to develop better diagnostics and drug therapies. Credit: Carlos Jones/ORNL, U.S. Dept. of Energy

ORNL researchers discovered genetic mutations that underlie autism using a new approach that could lead to better diagnostics and drug therapies.

ORNL’s RapidCure improves lithium-ion electrode production by producing electrodes faster, reducing the energy necessary for manufacturing and eliminating the need for a solvent recycling unit. Credit: Carlos Jones/ORNL, U.S. Dept. of Energy

Researchers at the Department of Energy’s Oak Ridge National Laboratory and their technologies have received seven 2022 R&D 100 Awards, plus special recognition for a battery-related green technology product.